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Incidence of oral thrush in patients with COPD prescribed inhaled corticosteroids: Effect of drug, dose, and device.

Author: BatsiouMaria, BjermerLeif, Bosnic-AnticevichSinthia, ChrystynHenry, CifraAlessandra, DekhuijzenP N Richard, FletcherMonica, PapiAlberto, PriceDavid B, Rodríguez-RoisinRoberto, SorianoJoan B, WoodLucy

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

This historical, observational, matched cohort study assessed oral thrush incidence in COPD patients prescribed FDC ICS/LABA therapies. Patients prescribed FDC ICS/LABA had significantly greater odds of experiencing oral thrush than those prescribed long-acting bronchodilators alone (adjusted OR 2.18 [95% CI 1.84-2.59]). Significantly fewer patients prescribed BUD/FOR DPI developed oral thrush compared with FP/SAL DPI (OR 0.77 [0.63-0.94]).
Paper Details　
Original Abstract of the Article :
BACKGROUND AND AIMS: Little information is available on real-life occurrence of oral thrush in COPD patients treated with ICS. We investigated oral thrush incidence in COPD patients prescribed FDC ICS/LABA therapies and assessed whether it is modulated by the ICS type, dose, and delivery device. ME...See full text at original site
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引用元：
https://doi.org/10.1016/j.rmed.2016.09.015

データ提供：米国国立医学図書館（NLM）

Oral Thrush and Inhaled Corticosteroids: Navigating the Desert of Respiratory Health

Chronic obstructive pulmonary disease (COPD) is a chronic lung condition, like a relentless sandstorm that affects the airways. This study investigated the incidence of oral thrush in patients with COPD who use inhaled corticosteroids (ICS). The researchers analyzed data from a large database, looking for patterns in the occurrence of oral thrush among COPD patients. They found that ICS use increased the risk of oral thrush, particularly with high doses and specific types of ICS. The researchers also found that the type of delivery device (DPI vs. pMDI) could affect the risk of oral thrush. This study offers valuable insights for clinicians and patients, helping them navigate the desert of respiratory health with greater awareness of potential risks and effective management strategies.

Inhaled Corticosteroids: Balancing Benefits and Risks

The study highlights the importance of understanding the potential risks of ICS use, particularly the risk of oral thrush. It emphasizes the need to carefully consider the dose and type of ICS, as well as the delivery method, to minimize this risk and maximize the benefits of treatment.

Respiratory Health: A Journey Through the Desert

Managing respiratory conditions can be a challenging journey, like traversing a vast and unforgiving desert. Understanding your condition, seeking appropriate medical care, and adopting healthy lifestyle choices can help you navigate this journey with greater ease and resilience.

Dr.Camel's Conclusion

This study sheds light on the complexities of managing COPD, reminding us that even in the desert of respiratory health, careful navigation is essential. It emphasizes the importance of balancing the benefits and risks of different treatment options, allowing us to find a more sustainable path to better health. Remember, just like a camel navigating a harsh desert landscape, we must be aware of our surroundings, seek appropriate guidance, and make informed decisions to ensure our well-being.

Date :
  1. Date Completed 2018-01-16
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

27817816

DOI: Digital Object Identifier

10.1016/j.rmed.2016.09.015

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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