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Clinical features of CKD-MBD in Japan: cohort studies and registry.

Author: FujiiNaohiko, HamanoTakayuki, IsakaYoshitaka, SakaguchiYusuke

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Randomized controlled trials (RCTs) are considered the gold standard for evaluating medical treatments, but observational studies like cohort studies and registries can provide valuable information about risk factors and treatment effects. This review discusses the use of such studies in Japan to understand chronic kidney disease and mineral bone disease (CKD-MBD). Findings from these studies have informed the development of unique guidelines for Japanese CKD patients, reflecting their specific needs and characteristics.
Paper Details　
Original Abstract of the Article :
Randomized controlled trials (RCTs) are essential for evidence-based medicine; however, cohort studies and registries provide an important information about risk factors and, hence, shed light on the target of laboratory parameters. The uniqueness of the current Japanese CKD-MBD guidelines lies in t...See full text at original site
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引用元：
https://doi.org/10.1007/s10157-016-1367-4

データ提供：米国国立医学図書館（NLM）

CKD-MBD: A Comprehensive Approach to Managing Chronic Kidney Disease

Chronic kidney disease (CKD) is a growing health concern, often accompanied by mineral and bone disorders (MBD). Managing CKD-MBD requires a multifaceted approach, considering various risk factors and treatment options. This study investigates the clinical features of CKD-MBD in Japan, drawing on data from cohort studies and registries.

The study analyzes data from the Japan Renal Data Registry, revealing the prevalence of low vitamin D status and high fibroblast growth factor 23 (FGF23) levels among Japanese patients with CKD. The researchers highlight the unique aspects of Japanese CKD-MBD guidelines, particularly the lower target range for intact parathyroid hormone levels. The study also explores the association of FGF23 levels with cardiovascular complications, suggesting the inclusion of left ventricular hypertrophy (LVH) as a fourth component of CKD-MBD.

This study provides valuable insights into the specific characteristics of CKD-MBD in Japan, underscoring the importance of tailored treatment strategies based on regional differences and patient populations. The research emphasizes the role of observational studies in informing evidence-based guidelines and treatment protocols.

Navigating the Shifting Sands of CKD-MBD

This study is like a camel caravan exploring the diverse landscape of CKD-MBD, taking into account regional differences and patient populations. The researchers meticulously analyze data from cohort studies and registries, uncovering the unique characteristics of CKD-MBD in Japan.

Optimizing Care for CKD-MBD Patients

This research highlights the importance of personalized approaches to managing CKD-MBD. The study's findings emphasize the need for tailored treatment strategies that consider patient-specific factors and regional variations in disease prevalence and management practices.

Dr.Camel's Conclusion

The research on CKD-MBD is like a camel caravan traversing a vast desert of medical complexities. The researchers meticulously investigate the specific characteristics of CKD-MBD in Japan, providing valuable insights for optimizing treatment strategies and improving patient outcomes.

Date :
  1. Date Completed 2017-08-17
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

27942882

DOI: Digital Object Identifier

10.1007/s10157-016-1367-4

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Languages

English

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