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The drugs that mostly frequently induce acute kidney injury: a case - noncase study of a pharmacovigilance database.

Author: , ChoukrounGabriel, GaboriauLouise, GrasValérie, LiabeufSophie, MasmoudiKamel, MicallefJoelle, MoragnyJulien, PicardSylvie, Pierson-MarchandiseMarion

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study provides a comprehensive overview of drug-induced acute kidney injury (AKI) based on spontaneously reported adverse drug reactions (ADRs) in the French national pharmacovigilance database (FPVD).
Paper Details　
Original Abstract of the Article :
Acute kidney injury (AKI) is associated with a high hospitalization rate, accelerated long-term decline in kidney function and a high mortality rate. Adverse drug reactions (ADRs) constitute one of the most important modifiable factors in the context of AKI. Most studies of drug-induced AKI have foc...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427222/

データ提供：米国国立医学図書館（NLM）

Drug-Induced Acute Kidney Injury: A Silent Threat

Acute kidney injury (AKI) is a serious condition that can lead to significant health complications. This study investigates the role of adverse drug reactions (ADRs) in AKI, analyzing data from a national pharmacovigilance database. The authors identified the drugs most frequently associated with AKI, providing valuable insights into potential risk factors. This research highlights the importance of drug safety monitoring and emphasizes the need for proactive measures to prevent drug-induced AKI.

Understanding Drug-Induced AKI: A Vital Step

This study provides a comprehensive overview of drug-induced acute kidney injury, highlighting the drugs most frequently associated with this condition. These findings underscore the crucial role of drug safety monitoring and the need for careful consideration of potential risks associated with medication use. This research emphasizes the need for vigilance and proactive measures to prevent drug-induced AKI.

Navigating the Desert of Drug Safety

The desert of drug safety can be treacherous, filled with potential pitfalls. This study serves as a vital reminder of the importance of ongoing drug safety monitoring and the need for a proactive approach to managing medication-related risks. It's a crucial step in safeguarding patient health and preventing drug-induced AKI.

Dr.Camel's Conclusion

The desert of drug safety is a vast and complex landscape, requiring constant vigilance. This study emphasizes the importance of monitoring drug-induced acute kidney injury, a silent threat that can have serious consequences. It's a reminder to approach medication with caution and to be aware of potential risks.

Date :
  1. Date Completed 2018-03-12
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

28002877

DOI: Digital Object Identifier

PMC5427222

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