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Cutaneous Side Effects and Transepidermal Water Loss To Gefitinib: A Study of 11 Patients.
Author: ChandraFranky, GunawanHendra, SandionoDendi, SugiriUnwati, SuwarsaOki
Original Abstract of the Article :
Cutaneous side effects caused by epidermal growth factor receptor (EGFR) inhibitors occurred in 45-100% of patients which may lead to therapy modification or interruption. This study aimed to evaluate cutaneous side effects and transepidermal water loss (TEWL) values in non-small cell lung carcinoma...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336432/
データ提供:米国国立医学図書館(NLM)
Gefitinib and Skin Side Effects: A Closer Look at TEWL
This research delves into the world of epidermal growth factor receptor (EGFR) inhibitors, a class of medications used to treat certain types of cancer. It's like a journey into the intricate workings of the human body, exploring the effects of these powerful drugs on various tissues and organs. This study examines the cutaneous side effects and transepidermal water loss (TEWL) associated with gefitinib, a specific EGFR inhibitor. It's like a meticulous examination of desert sand dunes, analyzing their composition and identifying potential hazards.
Skin Sensitivity: A Common Side Effect of Gefitinib
The study found that cutaneous side effects, like skin rash and dryness, were common among patients receiving gefitinib. It's like a traveler encountering a sandstorm, experiencing temporary discomfort and irritation. The study also found that TEWL, a measure of skin barrier function, was significantly increased in patients receiving gefitinib, suggesting that the drug may compromise the skin's ability to retain moisture.
Managing Skin Side Effects: A Multi-pronged Approach
This study emphasizes the importance of monitoring skin side effects in patients receiving gefitinib. It's like a desert explorer keeping a watchful eye on the environment, adjusting their course to avoid potential hazards. The study suggests that managing these side effects may involve strategies like moisturizing the skin and avoiding harsh soaps, potentially reducing discomfort and improving patient quality of life.
Dr.Camel's Conclusion
This study highlights the importance of being aware of potential skin side effects associated with gefitinib. It's like preparing for a desert journey by packing essential supplies and learning to navigate potential challenges. By understanding these side effects and implementing appropriate management strategies, healthcare providers can ensure a more comfortable and effective treatment experience for their patients.
Date :
- Date Completed n.d.
- Date Revised 2020-10-01
Further Info :
Related Literature
English
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