Lasmiditan for the treatment of migraine.

Author: BorroMarina, CapiMatilde, CipollaFabiola, CurtoMartina, GentileGiovanna, LionettoLuana, MartellettiPaolo, NegroAndrea, de AndrésFernando

Paper Details 
Original Abstract of the Article :
Migraine is one of the most common diseases in the world, with high economical and subjective burden. Migraine acute therapy is nowadays based on specific and non-specific drugs but up to 40% of episodic migraineurs still have unmet treatment needs and over 35% do not benefit from triptans administr...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1080/13543784.2017.1280457

データ提供:米国国立医学図書館(NLM)

Lasmiditan: A Novel Approach to Migraine Treatment

Migraine, a debilitating condition, often leaves sufferers seeking effective relief. This study explores the potential of lasmiditan, a novel serotonin1F receptor agonist, as a treatment for acute migraine attacks. The researchers investigated the preclinical and clinical evidence for lasmiditan, focusing on its unique mechanism of action and its ability to inhibit trigeminal neural activation, a key factor in migraine pain. They found that lasmiditan demonstrated efficacy in reducing migraine symptoms, without the vasoconstrictive effects commonly associated with triptans. This suggests that lasmiditan could be a valuable treatment option for patients who do not respond well to traditional migraine medications.

A New Frontier in Migraine Treatment

This study offers hope for a new era in migraine treatment with the development of lasmiditan. Its novel mechanism of action, targeting the serotonin1F receptor, presents a unique approach to managing migraine pain. The absence of vasoconstrictive effects could be a significant advantage for patients who experience side effects from traditional triptans. This research highlights the potential of lasmiditan to provide relief for a large number of individuals suffering from migraine.

Migraine: A Desert of Pain

Imagine migraine as a relentless sandstorm, sweeping across the mind, causing intense pain and debilitating symptoms. Traditional migraine treatments are like temporary shelters, offering some respite from the storm. Lasmiditan, on the other hand, is like a new and innovative weather-control system, aiming to quell the storm at its source. This study's findings offer hope for a brighter future for migraine sufferers, with the potential for more effective and targeted treatments.

Dr.Camel's Conclusion

This study explores the exciting potential of lasmiditan as a novel treatment for acute migraine attacks. Its unique mechanism of action and lack of vasoconstrictive effects make it a promising alternative to traditional migraine medications. Further research is needed to fully understand its long-term efficacy and safety, but lasmiditan offers a glimmer of hope for a better future for migraine sufferers.

Date :
  1. Date Completed 2017-03-17
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

28076702

DOI: Digital Object Identifier

10.1080/13543784.2017.1280457

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.