Paper Details 
Original Abstract of the Article :
The aim of this study was to investigate microemulsion (ME) based topical delivery system for fenoprofen calcium (FPCa) to eliminate its oral gastrointestinal adverse effects. ME was prepared by the water titration method using oleic acid as oil phase, tween 80 as a surfactant and propylene glycol a...See full text at original site
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引用元:
https://doi.org/10.1080/08982104.2017.1281951

データ提供:米国国立医学図書館(NLM)

Microemulsions: A New Oasis for Topical Delivery of Fenoprofen Calcium

The field of drug delivery is constantly evolving, seeking ways to improve drug efficacy and minimize side effects. This study explores the potential of microemulsions (MEs) as a topical delivery system for fenoprofen calcium (FPCa), a nonsteroidal anti-inflammatory drug (NSAID) commonly used to treat pain and inflammation.

The study aimed to develop a ME-based topical delivery system for FPCa to overcome its oral gastrointestinal side effects. Researchers formulated different MEs using various components and evaluated their characteristics, drug release, and efficacy in reducing inflammation in rats. The optimized ME formulation exhibited a high transdermal flux and permeation rate, suggesting its potential for effective topical delivery of FPCa.

Microemulsions: A Promising Approach for Topical Drug Delivery

The study suggests that MEs can provide an effective alternative to oral administration for FPCa, minimizing gastrointestinal side effects while maximizing drug delivery to the target site. This could be a significant advantage for patients with pain and inflammation, allowing them to experience relief without the risk of stomach irritation.

Navigating the Desert of Drug Delivery: Finding New Paths

This study highlights the potential of microemulsions for topical drug delivery. It's like discovering a new oasis in the vast desert of drug delivery methods! The study's promising findings suggest that MEs could be a game-changer in the field, offering more effective and safer ways to deliver medications.

Dr.Camel's Conclusion

The desert of drug delivery is full of challenges and opportunities. This study offers a fresh perspective, revealing the potential of microemulsions to overcome the limitations of traditional methods. It's like finding a new path through the desert, leading to more effective and safer delivery of medications.

Date :
  1. Date Completed 2019-02-07
  2. Date Revised 2019-02-15
Further Info :

Pubmed ID

28081643

DOI: Digital Object Identifier

10.1080/08982104.2017.1281951

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Languages

English

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