Paper Details

  1. Home
  2. Paper Details

Real life experience with direct-acting antivirals agents against hepatitis C infection in elderly patients.

Author: CastroÁngeles, CidPurificación, DelgadoManuel, MargusinoLuis, MeijideHéctor, MenaÁlvaro, MoranoLuis, PedreiraJosé D, PernasBerta, PovedaEva, Rodríguez-OsorioIria, SuárezMarta, TabernillaAndrés

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

Direct-acting antivirals (DAAs) were found to be effective in treating elderly patients with hepatitis C virus (HCV) infection, achieving high sustained virological response (SVR12) rates of 88.3%. However, adverse events (AEs) were frequent (65%), particularly when protease inhibitors (PIs) were used.
Paper Details　
Original Abstract of the Article :
BACKGROUND: New direct-acting antivirals agents (DAAs) are very safe and well tolerated. OBJECTIVES: The purpose of this study is to analyse the efficacy and safety of DAAs in elderly patients, who have co-morbidities and are on chronic medications. STUDY DESIGN: All HCV-infected patients over 65 ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.jcv.2017.01.003

データ提供：米国国立医学図書館（NLM）

Treating Hepatitis C in the Elderly: A Tale of Two Hospitals

The field of medicine is constantly evolving, just like the shifting sands of the desert. This study examines the efficacy and safety of direct-acting antivirals (DAAs) in elderly patients with Hepatitis C. They're like seasoned travelers navigating the complex landscape of chronic diseases, seeking effective treatments for a growing population. Their research is a testament to the remarkable progress made in the fight against Hepatitis C, and their findings are crucial for ensuring that older individuals also benefit from these advancements.

DAAs: A New Oasis in the Desert of Hepatitis C

Their findings show that DAAs are highly effective in elderly patients, achieving high rates of sustained virological response. This is like discovering a new oasis in the desert, offering a chance for healing and restoration. This research is a beacon of hope for older individuals with Hepatitis C, demonstrating that effective treatments are available and providing a path towards a healthier future.

Living Well With Hepatitis C: A Journey Through the Desert

Living with chronic conditions can be challenging, but this research offers a ray of hope. It demonstrates that older individuals with Hepatitis C can access effective treatments and achieve long-term remission. This research is a reminder that we must continue to innovate and develop new therapies, ensuring that everyone, regardless of age, has access to the care they need.

Dr.Camel's Conclusion

This study is a testament to the incredible progress made in the fight against Hepatitis C. It shows that effective treatments are now available for older individuals, offering a chance for a healthier and longer life. Like a seasoned traveler navigating the desert, researchers are continuing to explore new paths and discover new solutions, bringing hope and healing to those in need. This research is a reminder that the journey towards a healthier future is ongoing, and we must continue to strive for progress in all aspects of healthcare.

Date :
  1. Date Completed 2018-01-03
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

28183063

DOI: Digital Object Identifier

10.1016/j.jcv.2017.01.003

Related Literature

Article Analysis
・Side Effects of ombitasvir paritaprevir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.