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Effects of dabigatran according to age in atrial fibrillation.

Author: ConnollyStuart J, CoppensMichiel, EikelboomJohn W, EzekowitzMichael, LauwMandy N, NakamyaJuliet, OldgrenJonas, WallentinLars, WangJia, YusufSalim

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study analyzed the effects of dabigatran versus warfarin on stroke, bleeding, and mortality in patients with atrial fibrillation across different age groups. The findings show that dabigatran may offer advantages over warfarin in older patients with atrial fibrillation.
Paper Details　
Original Abstract of the Article :
The prevalence of atrial fibrillation (AF) and the risk of stroke and bleeding vary according to age. To estimate effects of dabigatran, compared with warfarin, on stroke, bleeding and mortality in patients with AF in the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial accordi...See full text at original site
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引用元：
https://doi.org/10.1136/heartjnl-2016-310358

データ提供：米国国立医学図書館（NLM）

Dabigatran: A Tailored Approach to Atrial Fibrillation

Atrial fibrillation (AF), a common heart rhythm disorder, poses a significant risk of stroke and bleeding. This research examines the effects of dabigatran, a novel oral anticoagulant, compared to warfarin in patients with AF, focusing on the impact of age on treatment outcomes. The study meticulously analyzes the data from the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial, investigating the efficacy and safety of dabigatran across different age groups. This research is like a skilled navigator charting a course through the complexities of AF, considering the unique needs of different patient populations.

Dabigatran: A Personalized Approach to Stroke Prevention

The research provides valuable insights into the potential benefits and risks of dabigatran in patients with AF, emphasizing the importance of considering age as a key factor in treatment decisions. The study findings suggest that dabigatran may offer a safe and effective alternative to warfarin for stroke prevention in patients with AF, but the risk of bleeding may vary depending on age.

A Journey Through the Desert of Heart Health

This research underscores the importance of a personalized approach to managing AF, taking into account the specific needs and risks of each individual patient. The study findings highlight the potential benefits and challenges of dabigatran, emphasizing the need for careful monitoring and individualized treatment strategies. It is like navigating a vast desert landscape, where each traveler requires a unique approach to ensure a safe and successful journey.

Dr.Camel's Conclusion

This research offers valuable insights into the complex interplay between age and anticoagulant therapy in patients with AF. It underscores the need for a personalized approach to managing this condition, taking into account the specific needs and risks of each individual patient. It is a reminder that the desert of heart health is a diverse and challenging landscape, requiring careful navigation and a commitment to personalized care.

Date :
  1. Date Completed 2017-08-09
  2. Date Revised 2018-01-26
Further Info :

Pubmed ID

28213368

DOI: Digital Object Identifier

10.1136/heartjnl-2016-310358

Related Literature

Article Analysis
・Effects of dabigatran
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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