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Diagnosis and Treatment of Non-24-h Sleep-Wake Disorder in the Blind.
Author: EastmanCharmane I, EmensJonathan S
Original Abstract of the Article :
Non-24-h sleep-wake disorder (non-24) is a circadian rhythm disorder occurring in 55-70% of totally blind individuals (those lacking conscious light perception) in which the 24-h biological clock (central, hypothalamic, circadian pacemaker) is no longer synchronized, or entrained, to the 24-h day. I...See full text at original site
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引用元:
https://doi.org/10.1007/s40265-017-0707-3
データ提供:米国国立医学図書館(NLM)
Non-24-h Sleep-Wake Disorder: Navigating the Desert of Circadian Rhythms
Disruptions in our internal clocks, known as circadian rhythms, can lead to sleep-wake disorders. This research focuses on non-24-h sleep-wake disorder (non-24), a condition that affects a significant proportion of individuals who are totally blind. The study delves into the intricacies of the circadian clock, which regulates sleep-wake cycles, akin to a compass guiding a camel through the vast desert. Non-24 occurs when this internal clock is no longer synchronized with the 24-hour day, leading to persistent daytime sleepiness and nighttime insomnia. The authors explore the potential of melatonin and the melatonin agonist tasimelteon as treatments for non-24, aiming to re-entrain the circadian clock to a more normal rhythm.
Finding the Oasis of Regular Sleep in Non-24
This study provides valuable insights into the management of non-24, highlighting the importance of carefully timing melatonin or tasimelteon administration to optimize treatment effectiveness. The study's findings offer hope for individuals suffering from this challenging condition, like discovering a hidden oasis in the desert of sleep disruption. The authors' emphasis on individualized treatment approaches reflects the need for a personalized approach to managing circadian rhythm disorders.
A Guide to Navigating the Desert of Sleep
This research underscores the importance of understanding our internal clocks and their role in maintaining healthy sleep patterns. The desert of sleep can be a challenging landscape, but with knowledge and appropriate interventions, we can find our way to a restful oasis.
Dr.Camel's Conclusion
Non-24-h sleep-wake disorder presents a challenging desert of sleep disruption. This study offers a roadmap for navigating this challenging terrain, highlighting the importance of melatonin and personalized treatment approaches. With a little guidance, we can find the oasis of regular sleep and restore balance to our circadian rhythms.
Date :
- Date Completed 2017-05-02
- Date Revised 2018-11-13
Further Info :
Related Literature
English
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