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Bioavailability of a dexlansoprazole delayed-release orally disintegrating tablet: effects of food and mode of administration.

Author: KukulkaMichael, NudurupatiSai, PerezMaria Claudia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study found that the AUC from the dexlansoprazole ODT was equivalent when administered in the fed and fasted states. Equivalent systemic exposure to dexlansoprazole was achieved regardless of the administration route.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Dexlansoprazole is a proton pump inhibitor (PPI) approved for use in dual delayed-release capsule and orally disintegrating tablet (ODT) formulations. AIM: To assess effects of food, water, and route of administration on the bioavailability of dexlansoprazole 30-mg ODT. METHODS: Two se...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323062/

データ提供：米国国立医学図書館（NLM）

Dexlansoprazole: A Versatile Tool in the Fight Against Stomach Acid

This research explores the [pharmacokinetics of dexlansoprazole], a medication used to [reduce stomach acid] – a critical area of research for patients with [gastrointestinal disorders]. This study delves into the [bioavailability of dexlansoprazole] when administered in different ways, including [with or without food] and through various routes like [oral syringe, nasogastric tube, and swallowing intact]. The findings provide valuable insights into how the body processes this medication, informing optimal treatment strategies.

A Reliable and Flexible Solution

The research found that [dexlansoprazole] achieves equivalent systemic exposure regardless of how it’s administered. This suggests that [dexlansoprazole is a reliable and flexible treatment option] for patients with [acid reflux and other related conditions]. This flexibility is particularly important for patients who might have difficulty swallowing or require alternative methods of medication administration.

Managing Your Stomach Acid: A Practical Approach

Just like a camel can navigate the desert and adapt to different conditions, [dexlansoprazole] is a versatile medication that can be adapted to individual needs. The research highlights that [the method of administration doesn’t significantly affect its effectiveness]. This means that patients can have more flexibility in how they take their medication, making it easier to manage their condition and maintain a good quality of life.

Dr.Camel's Conclusion

This research is like a comforting oasis in the desert of stomach acid discomfort. It shows that [dexlansoprazole] is a reliable and adaptable treatment option that can be tailored to individual needs. The findings highlight the importance of understanding how medication is processed in the body, allowing us to make informed choices for optimal treatment outcomes.
Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

28255251

DOI: Digital Object Identifier

PMC5323062

Related Literature

Article Analysis
・Effects of dexlansoprazole
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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