Salsalate improves glycaemia in overweight persons with diabetes risk factors of stable statin-treated cardiovascular disease: A 30-month randomized placebo-controlled trial.

Author: , DesaiTanvi, FowlerKristen, GoldfineAllison B, HauserThomas, JosephStacey, SalastekarNinad, SchaeferErnst J, ShoelsonSteven E

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To assess long-term efficacy and safety of salsalate to improve glycemia in persons with diabetes risk, who are overweight with statin-treated, stable coronary heart disease. METHODS: Glycemic status was assessed in 192 persons without diabetes at baseline in a pre-specified secondary an...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/28295931

データ提供:米国国立医学図書館(NLM)

Salsalate: A Promising Ally in Diabetes Prevention

Diabetes is a growing public health concern, and finding effective strategies for preventing this disease is crucial. This research investigates the potential of salsalate, a non-steroidal anti-inflammatory drug, to improve glycemia in overweight individuals with diabetes risk factors, specifically those with stable, statin-treated cardiovascular disease. The researchers conducted a 30-month randomized, placebo-controlled trial and found that salsalate significantly improved glycemic control in the study participants. While the study highlights the potential benefits of salsalate for diabetes prevention, the authors note that renal safety concerns may limit its clinical application.

Salsalate: A Potential Tool for Diabetes Prevention

The study's findings suggest that salsalate could be a promising therapeutic option for preventing type 2 diabetes in individuals at risk. The drug's ability to improve glycemic control in overweight individuals with diabetes risk factors is encouraging, and further research is needed to explore its potential benefits and to address the concerns regarding renal safety.

Navigating the Diabetes Landscape

Imagine the world of diabetes as a complex and challenging landscape, with various obstacles and challenges to overcome. This research, like a skilled explorer, investigates a new path, exploring the potential of salsalate as a tool for preventing this disease. The findings suggest that salsalate could serve as a valuable guide, potentially helping individuals navigate the terrain of diabetes risk and improve their chances of avoiding this debilitating condition.

Dr. Camel's Conclusion

Diabetes prevention is a critical public health goal, and research continues to uncover new strategies for mitigating this growing threat. This study provides encouraging evidence for the potential of salsalate as a tool for improving glycemic control and potentially preventing type 2 diabetes in at-risk individuals. While further research is needed to address concerns regarding renal safety, the findings of this study offer hope for individuals seeking to prevent this disease and improve their overall health.

Date :
  1. Date Completed 2018-07-12
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

28295931

DOI: Digital Object Identifier

NIHMS862052

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Languages

English

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