Comparison of intravaginal 6.5mg (0.50%) prasterone, 0.3mg conjugated estrogens and 10μg estradiol on symptoms of vulvovaginal atrophy.

Author: ArcherDavid F, LabrieFernand, MartelCéline, MontesinoMarlene

Paper Details 
Original Abstract of the Article :
The objective is to compare the effect of intravaginal dehydroepiandrosterone (DHEA, prasterone), conjugated equine estrogens (CEE) and estradiol (E<sub>2</sub>) on moderate to severe dyspareunia and/or vaginal dryness. In a review of available data, independent prospective, randomized, double-blind...See full text at original site
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引用元:
https://doi.org/10.1016/j.jsbmb.2017.03.014

データ提供:米国国立医学図書館(NLM)

Vulvovaginal Atrophy: Exploring New Oasis of Relief in the Desert of Menopause

Vulvovaginal atrophy (VVA), a common condition associated with menopause, can significantly impact a woman's sexual health and quality of life. This review article compares the effectiveness of three intravaginal treatments for VVA: prasterone (DHEA), conjugated equine estrogens (CEE), and estradiol (E2). The authors, like explorers seeking a new oasis of relief in the desert of menopause, examine the available research on these treatments and their impact on VVA symptoms, particularly dyspareunia and vaginal dryness.

Treatment Efficacy: A New Oasis of Relief in the Desert of VVA

The review highlights the potential of intravaginal prasterone as an effective treatment for VVA. The authors found that daily administration of 6.5 mg (0.50%) prasterone appears to be at least as efficacious as 0.3 mg CEE or 10 microg E2 for relieving dyspareunia and vaginal dryness. This suggests that prasterone could offer a new oasis of relief for women experiencing VVA.

Navigating the Desert of Menopause: Finding Relief and Wellness

This review underscores the importance of addressing VVA symptoms and improving the quality of life for women experiencing menopause. The authors highlight the potential benefits of intravaginal prasterone as a treatment option for VVA, providing an alternative to estrogen-based therapies. This research offers a valuable tool for navigating the often challenging journey through menopause.

Dr.Camel's Conclusion

VVA is a common condition that can significantly impact women's well-being. This review provides a valuable overview of treatment options, highlighting the potential of intravaginal prasterone as a safe and effective alternative for women seeking relief from VVA symptoms.

Date :
  1. Date Completed 2017-11-13
  2. Date Revised 2017-12-08
Further Info :

Pubmed ID

28323042

DOI: Digital Object Identifier

10.1016/j.jsbmb.2017.03.014

Related Literature

SNS
PICO Info
in preparation
Languages

English

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