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Blood derived products in pediatrics: New laboratory tools for optimizing potency assignment and reducing side effects.

Author: AmiralJean, SeghatchianJerard

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article discusses the progress in blood-derived therapies for neonates and children with rare bleeding disorders. The introduction of recombinant proteins has reduced the risks associated with plasma-extracted products. Laboratory methods contribute to minimizing the side effects of blood cell concentrates, derived plasma products, and therapeutic recombinant proteins.
Paper Details　
Original Abstract of the Article :
Neonates and children can develop rare bleeding disorders due to congenital/acquired coagulation Factor deficiencies, or allo-immune/autoimmune complications, or can undergo surgeries at high haemorrhagic risk. They then need specialized transfusion of blood components/products, or purified blood ex...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/j.transci.2017.03.004

データ提供：米国国立医学図書館（NLM）

Blood Derived Products: A Journey of Innovation in Pediatric Healthcare

This research delves into the fascinating world of blood-derived products, exploring the latest advances in their production, quality control, and clinical applications, particularly in pediatric healthcare. The authors highlight the challenges and opportunities associated with using blood-derived products in managing various bleeding disorders, congenital deficiencies, and surgical procedures in infants and children. This research contributes to the ongoing efforts to enhance the safety and efficacy of blood-derived therapies, optimizing treatment outcomes for pediatric patients.

New Laboratory Tools: Optimizing Potency and Reducing Side Effects

The research emphasizes the importance of advanced analytical methods and biotechnology in optimizing the manufacturing processes for blood-derived products. This focus on quality control ensures the production of safe and effective products while minimizing the occurrence of side effects. The study highlights the role of laboratory tools in identifying potential contaminants and optimizing storage conditions, ultimately contributing to improved patient safety and treatment outcomes.

Ensuring Safety and Efficacy in Pediatric Blood-Derived Therapies

This research underscores the critical importance of prioritizing the safety and efficacy of blood-derived products in pediatric healthcare. The findings highlight the ongoing efforts to refine manufacturing processes and quality control measures, ensuring the production of high-quality products that minimize the risk of adverse events. The research emphasizes the need for continued investment in research and development to further enhance the safety and efficacy of blood-derived therapies for pediatric patients.

Dr. Camel's Conclusion

Just as a camel adapts to the harsh desert environment, scientists are constantly adapting and innovating in the field of blood-derived products. This research highlights the importance of advanced laboratory tools and quality control measures in ensuring the safety and efficacy of these vital therapies for pediatric patients. The findings underscore the commitment to providing safe and effective treatment options for children, ultimately improving their health and well-being.

Date :
  1. Date Completed 2018-02-20
  2. Date Revised 2018-02-20
Further Info :

Pubmed ID

28343935

DOI: Digital Object Identifier

10.1016/j.transci.2017.03.004

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・Effective treatment of pediatrics
SNS
PICO Info
in preparation
Languages

English

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