Differential clinical pharmacology of rolapitant in delayed chemotherapy-induced nausea and vomiting (CINV).

Author: Abdel-RahmanOmar, RashadNoha

Paper Details 
Original Abstract of the Article :
Rolapitant is a highly selective neurokinin-1 receptor antagonist, orally administered for a single dose of 180 mg before chemotherapy with granisetron D1, dexamethasone 8 mg BID on day 2-4. It has a unique pharmacological characteristic of a long plasma half-life (between 163 and 183 hours); this l...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373840/

データ提供:米国国立医学図書館(NLM)

Rolapitant: A New Frontier in Nausea and Vomiting Management

Chemotherapy, a powerful weapon against cancer, can often come with debilitating side effects, including nausea and vomiting. This research delves into the potential of rolapitant, a highly selective neurokinin-1 receptor antagonist, for managing chemotherapy-induced nausea and vomiting (CINV). The study examines the unique pharmacological characteristics of rolapitant, its clinical efficacy, and safety profile, offering valuable insights into its potential role in CINV management. This research is like a team of scientists exploring a new desert oasis, seeking to uncover a safe and effective solution to a challenging medical problem.

Rolapitant: A Promising Solution for Chemotherapy-Induced Nausea

The research highlights the impressive efficacy of rolapitant in managing delayed CINV, a common and often debilitating side effect of chemotherapy. The study findings suggest that rolapitant, when administered in a single dose of 180 mg before chemotherapy, can effectively control delayed emesis and improve the overall quality of life for patients undergoing chemotherapy. This research underscores the potential of rolapitant to significantly improve the patient experience during chemotherapy.

A Desert of Discomfort: Seeking Relief from Nausea

This research provides valuable insights into the potential benefits of rolapitant for managing CINV. The study findings suggest that rolapitant offers a safe and effective way to reduce nausea and vomiting, improving the overall quality of life for patients undergoing chemotherapy. It is like discovering a hidden oasis in the vast and challenging desert of cancer treatment, providing a much-needed source of relief from the discomfort associated with this debilitating side effect.

Dr.Camel's Conclusion

This research offers a promising new approach to managing CINV, highlighting the potential of rolapitant to improve the quality of life for patients undergoing chemotherapy. It is a testament to the ongoing efforts of researchers to develop innovative and effective treatments for the debilitating side effects associated with cancer therapy.

Date :
  1. Date Completed 2017-05-05
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

28392676

DOI: Digital Object Identifier

PMC5373840

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.