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Clinical evaluation of methylcellulose as a bulk laxative.

Author: BassP, BurdickB B, HamiltonJ W, WagnerJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Methylcellulose effectively increased fecal weight and frequency in both normal subjects and chronically constipated individuals. Doses as low as 1 g showed significant laxative effect.
Paper Details　
Original Abstract of the Article :
We studied a bulk laxative containing methylcellulose in a group of normal subjects as well as in a group of chronically constipated individuals. The initial study in normal subjects was performed to show that the compound could increase fecal weight without significant side effects. Fifty healthy s...See full text at original site
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引用元：
https://doi.org/10.1007/BF01535996

データ提供：米国国立医学図書館（NLM）

Methylcellulose: An Effective Bulk Laxative

Constipation, a common digestive issue, can be a source of discomfort and frustration. This study examines the effectiveness of methylcellulose, a bulk-forming laxative, in treating constipation. Researchers conducted two phases of study, first evaluating methylcellulose in healthy individuals and then in individuals with chronic constipation.

Methylcellulose: A Gentle and Effective Solution

The study found that methylcellulose, even in low doses, effectively increased stool frequency and water content, demonstrating its effectiveness as a laxative. The researchers found no increase in individual stool weight, suggesting that methylcellulose is a gentle and effective treatment option for constipation. This study provides evidence supporting the use of methylcellulose as a safe and well-tolerated bulk laxative.

Navigating the Digestive Desert: Finding Relief Through Fiber

This research highlights the importance of dietary fiber in maintaining healthy digestion. The findings suggest that methylcellulose, a source of soluble fiber, can effectively address constipation by increasing stool bulk and facilitating smooth bowel movements. This study emphasizes the importance of incorporating fiber-rich foods and supplements into a balanced diet.

Dr.Camel's Conclusion

This study, like a caravan finding a hidden oasis in the vast desert, reveals the effectiveness of methylcellulose in addressing constipation. The findings demonstrate its ability to gently and effectively restore regular bowel function, offering relief to individuals navigating the challenges of digestive discomfort.
Date :
  1. Date Completed 1988-08-19
  2. Date Revised 2019-07-21
Further Info :

Pubmed ID

2839321

DOI: Digital Object Identifier

10.1007/BF01535996

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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