Rationalisation of regimens of treatment of kala-azar with sodium stibogluconate in India: a randomised study.

Author: KumarM, KumarP, MishraB N, PandeyA K, ThakurC P

Paper Details 
Original Abstract of the Article :
The efficacy and safety of six regimens of treatment for kala-azar (visceral leishmaniasis) with sodium stibogluconate were evaluated in a prospective randomised study to ascertain the optimal treatment for Indian patients. Altogether 371 patients with kala-azar were randomised to receive sodium sti...See full text at original site
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引用元:
https://doi.org/10.1136/bmj.296.6636.1557

データ提供:米国国立医学図書館(NLM)

Finding the Right Path to Cure Kala-azar: A Randomized Study

Kala-azar, or visceral leishmaniasis, is a debilitating parasitic disease, a silent threat lurking in the desert of human health. This study investigates the effectiveness and safety of different treatment regimens using sodium stibogluconate in patients with kala-azar. It's like exploring different routes through a desert, seeking the most effective path to cure this illness. Researchers meticulously analyzed 371 patients, randomizing them to receive sodium stibogluconate in varying doses and durations. The study found that the highest dose (20 mg/kg) administered for the longest duration (40 days) yielded the highest cure rate with minimal toxicity. This discovery offers a crucial roadmap for navigating the challenges of kala-azar treatment.

The Optimal Route: Navigating Kala-azar Treatment

This study provides valuable insights into the most effective treatment strategy for kala-azar. The researchers' findings highlight the importance of dosage and duration in achieving optimal cure rates. It's like choosing the most reliable caravan route through the desert, ensuring a successful journey to recovery. The study's focus on minimizing toxicity further underscores the importance of finding a balanced approach to treatment, optimizing both effectiveness and safety.

Navigating the Desert of Parasitic Diseases: A Call to Action

This research underscores the need for continued research and development of effective treatments for parasitic diseases like kala-azar. It's like exploring new pathways and finding new sources of water in the vast desert of parasitic infections. The study's findings provide a valuable blueprint for optimizing treatment regimens, ensuring the best possible outcomes for patients battling this debilitating illness.

Dr. Camel's Conclusion

This study shines a light on the importance of finding the right path to cure kala-azar, highlighting the effectiveness of sodium stibogluconate when administered in optimal doses and durations. It's like discovering a reliable oasis in the desert, providing a source of hope and healing for those affected by this disease. This research encourages further exploration of treatment options, ensuring a brighter future for patients facing the challenges of kala-azar.

Date :
  1. Date Completed 1988-09-01
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

2840172

DOI: Digital Object Identifier

10.1136/bmj.296.6636.1557

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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