Paper Details

  1. Home
  2. Paper Details

Prophylactic efficacy of primaquine for preventing Plasmodium falciparum and Plasmodium vivax parasitaemia in travelers: A meta-analysis and systematic review.

Author: AzimiSara, HaghdoustAli Akbar, HashemiSaeed, KhosraviNasim, KolifarhoodGoodarz, KondrashinAnatoly, Masoumi-AslHossein, Mozafar SaadatiHossein, RaeisiAhmad, RanjbarMansour, SchapiraAllan

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review and meta-analysis evaluated the prophylactic effectiveness and toxicity of primaquine for malaria chemoprophylaxis. The authors found that primaquine has high prophylactic efficacy, but further research is needed to compare its effectiveness and toxicity with other malaria chemoprophylaxis regimens.
Paper Details　
Original Abstract of the Article :
With increased international travel over the world the need for safe and effective chemoprophylaxis for malaria is as great as ever. The choice of regimen is difficult, as effectiveness should be weighted against potential adverse effects. Although, some studies have reported high prophylactic effic...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.tmaid.2017.04.005

データ提供：米国国立医学図書館（NLM）

Primaquine: A Potential Prophylactic for Malaria Prevention in Travelers

This systematic review and meta-analysis investigates the prophylactic efficacy of primaquine in preventing Plasmodium falciparum and Plasmodium vivax parasitemia in travelers. The authors reviewed various studies and found that primaquine demonstrated high prophylactic efficacy against malaria, but also noted the importance of considering potential adverse effects. The study emphasizes the need for careful evaluation of both efficacy and safety when selecting malaria prophylaxis regimens for travelers.

Primaquine: A Promising Prophylactic Option for Malaria Prevention

The study's findings suggest that primaquine holds promise as a prophylactic agent for malaria prevention in travelers. The observed high efficacy against both Plasmodium falciparum and Plasmodium vivax highlights its potential as a valuable tool in minimizing the risk of malaria infection during travel. However, the importance of balancing efficacy with potential adverse effects is also emphasized.

Staying Safe While Traveling: Choosing the Right Malaria Prophylaxis

This research underscores the importance of carefully considering all available options and consulting with a healthcare professional when choosing malaria prophylaxis for travel. The study highlights the need for a comprehensive evaluation of both efficacy and safety when making this important decision. Remember, protecting yourself from malaria while traveling is crucial, and choosing the right prophylaxis can play a significant role in mitigating risks.

Dr. Camel's Conclusion

This systematic review and meta-analysis provides valuable insights into the prophylactic efficacy of primaquine in preventing malaria. The study's findings highlight the potential benefits of primaquine, but also emphasize the need for careful consideration of both efficacy and potential adverse effects when selecting malaria prophylaxis for travelers. Consulting with a healthcare professional is crucial in making an informed decision about the most appropriate prophylactic regimen for your specific travel plans.

Date :
  1. Date Completed 2017-10-24
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28450185

DOI: Digital Object Identifier

10.1016/j.tmaid.2017.04.005

Related Literature

Article Analysis
・Effects of primaquine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.