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Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses.
Author: BoralSengül, BörnoS, DelebinskiC I, EggertA, JägerS, MeierhoferD, SeifertG, TimmermannB, TwardziokM
Original Abstract of the Article :
The hydrophobic triterpenes, oleanolic and betulinic acid as well as the hydrophilic mistletoe lectins and viscotoxins possess anticancer properties. They do all occur in combination in European mistletoe (Viscum album L.). Commercial Viscum album L. extracts are aqueous, excluding the insoluble tri...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410041/
データ提供:米国国立医学図書館(NLM)
Mistletoe Extract's Impact on Ewing Sarcoma Cells
This study explores the potential of a defined European mistletoe extract as a therapeutic agent against Ewing sarcoma, a rare and aggressive type of bone cancer. Researchers investigated the molecular mechanisms underlying the extract's anticancer effects by examining changes in gene expression and protein levels within Ewing sarcoma cells. The study revealed that mistletoe extract triggers cellular stress responses, suggesting a mechanism by which it may effectively combat cancer cells.
Mistletoe Extract's Anticancer Potential
This study provides evidence that mistletoe extract holds promise as a potential therapeutic agent for Ewing sarcoma. The extract's ability to induce cellular stress responses in cancer cells suggests a unique and potentially effective anticancer mechanism. These findings warrant further investigation to explore the clinical applications of mistletoe extract for Ewing sarcoma treatment.
Exploring Alternative Cancer Therapies
This research highlights the potential of natural products like mistletoe extract in cancer treatment. It encourages further investigation into the efficacy and safety of these alternative therapies, which could offer new options for patients battling cancer. The study also emphasizes the importance of understanding the molecular mechanisms underlying the effects of these agents to optimize their therapeutic use.
Dr.Camel's Conclusion
Just as a desert oasis provides life-sustaining water to thirsty travelers, mistletoe extract may offer a glimmer of hope for patients battling Ewing sarcoma. This research, like a camel caravan exploring a hidden oasis, reveals the potential of mistletoe extract as a valuable resource in the fight against cancer. It's a reminder that nature's secrets hold the key to unlocking new treatments for challenging diseases.
Date :
- Date Completed 2017-07-31
- Date Revised 2023-11-12
Further Info :
Related Literature
English
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