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Effectiveness of treatments for medication-related osteonecrosis of the jaw: A systematic review and meta-analysis.

Author: AzarpazhoohAmir, El-RabbanyMohamed, LamDavid K, SgroAdam, ShahPrakeshkumar S

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Surgical treatment of medication-related osteonecrosis of the jaw (MRONJ) was associated with higher odds of complete resolution of the condition compared with medical treatment. High-quality research is required for conclusive statements to be made regarding treatment strategies for management of MRONJ.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The effectiveness of management strategies used for the treatment of medication-related osteonecrosis of the jaw (MRONJ) remains poorly understood. The authors evaluated systematically the effectiveness of the various treatment modalities used for MRONJ. TYPES OF STUDIES REVIEWED: The a...See full text at original site
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引用元：
https://doi.org/10.1016/j.adaj.2017.04.002

データ提供：米国国立医学図書館（NLM）

Navigating the Complexities of MRONJ: Exploring Treatment Options

Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication associated with certain medications, particularly bisphosphonates. Researchers are working to understand the best approaches for managing MRONJ, seeking effective and safe treatment options. This study reviews the current evidence on the effectiveness of various treatment modalities for MRONJ, seeking to guide clinicians in providing optimal care for their patients.

Surgery: A Potential Pathway to Resolution

This comprehensive review, like a seasoned navigator charting a course through a treacherous landscape, examined the evidence on the effectiveness of different MRONJ treatments. While the study found that surgery was associated with a higher likelihood of complete resolution compared to medical management, it also highlighted the need for more robust research with high-quality data to definitively determine the optimal treatment approach.

Understanding MRONJ: A Complex Journey Towards Resolution

This study underscores the complexity of MRONJ and the need for more research to guide treatment decisions. It's like navigating a dense forest, where multiple paths lead to different outcomes. This study provides valuable insights into the current state of knowledge, but further research is needed to definitively determine the best treatment options for this challenging condition.

Dr.Camel's Conclusion

The management of MRONJ is a complex and evolving area of medicine. This review highlights the need for more research to provide clear guidance on the best treatment options for this challenging condition. It's a reminder that the journey towards a healthier future is often paved with uncertainty, but with persistent research and a commitment to finding solutions, we can continue to improve patient outcomes and provide better care for those affected by this challenging disease.

Date :
  1. Date Completed 2018-10-18
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28527518

DOI: Digital Object Identifier

10.1016/j.adaj.2017.04.002

Related Literature

Article Analysis
・Effective treatment of osteonecrosis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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