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An Inter-Ethnic Comparison Study of Ziprasidone Plasma Levels, Dosage and Clinical Response in Patients with Schizophrenia.
Author: ChenLixia, HuangXiaojun, LvDongsheng, YangQing, YuDongsheng, YunXiaobin, ZhaoMeirong
Original Abstract of the Article :
OBJECTIVE: The aim of this study was to investigate ziprasidone plasma concentration, daily dose and clinical efficacy and safety in Han Chinese and Mongolian patients with first-episode schizophrenia. METHODS: A total of 123 inpatients affected by schizophrenia were recruited from the Mental Healt...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440439/
データ提供:米国国立医学図書館(NLM)
Schizophrenia Treatment: Exploring Ethnic Differences in Ziprasidone Response
The world of mental health is like a complex desert, filled with diverse landscapes and challenges. This study focuses on schizophrenia, a complex brain disorder, exploring the potential impact of ethnicity on the response to ziprasidone, an antipsychotic medication. The researchers conducted a study involving 123 inpatients with first-episode schizophrenia, comparing Han Chinese and Mongolian patients. They analyzed ziprasidone plasma concentration, daily dosage, clinical efficacy, and safety outcomes over a six-week period. This research investigates the potential influence of ethnicity on medication response and the need for personalized treatment approaches.
Unveiling Ethnic Differences: Ziprasidone Response in Han Chinese and Mongolian Patients
The study reveals significant ethnic differences in the response to ziprasidone. Mongolian patients, on average, required higher doses of ziprasidone to achieve effective symptom control compared to Han Chinese patients. This finding suggests potential differences in drug metabolism and clearance between these ethnic groups. It's like encountering different landscapes in the desert, requiring adjustments to navigate effectively. This research highlights the importance of considering ethnic background and potentially adjusting treatment strategies accordingly.
A Personalized Approach to Mental Health Care: Addressing Ethnic Diversity
This study underscores the importance of personalized approaches to mental health care, taking into account factors like ethnicity and genetic background. It's like a skilled desert guide, customizing routes and strategies based on the unique characteristics of the terrain. By understanding the potential influence of ethnicity on medication response, healthcare professionals can tailor treatment plans to individual patients, optimizing outcomes and promoting better health outcomes. This research encourages a more nuanced approach to mental health care, embracing the diversity of our patients and their unique needs.
Dr. Camel's Conclusion
This study sheds light on the intricate interplay of ethnicity and medication response in schizophrenia. It's like exploring a vast desert with diverse landscapes, each requiring a unique approach to navigate effectively. The findings highlight the importance of personalized treatment strategies, taking into account factors like ethnicity to ensure optimal outcomes for patients with schizophrenia.
Date :
- Date Completed n.d.
- Date Revised 2020-09-30
Further Info :
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