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Device-Aided Treatment Strategies in Advanced Parkinson's Disease.

Author: AntoniniAngelo, DatievaVeronika, NituBianca, OdinPer, TimpkaJonathan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review explores the effectiveness of device-aided therapies, including deep brain stimulation (DBS), levodopa-carbidopa intestinal gel infusion (LCIG), and subcutaneous apomorphine infusion, for managing motor fluctuations and dyskinesia in advanced Parkinson's disease. While these therapies show similar efficacy in reducing "off time" and dyskinesia, they differ significantly in their side effects and complications.
Paper Details　
Original Abstract of the Article :
With peroral levodopa treatment, a majority of patients develop motor fluctuations and dyskinesia already within a few years of therapy. Device-aided Parkinson (PD) therapies refer to deep brain stimulation (DBS), levodopa-carbidopa intestinal gel infusion (LCIG), and subcutaneous infusion of the do...See full text at original site
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引用元：
https://doi.org/10.1016/bs.irn.2017.03.001

データ提供：米国国立医学図書館（NLM）

Device-Aided Treatment Strategies in Advanced Parkinson's Disease: Navigating the Desert of Motor Fluctuations

This study examines the use of device-aided therapies, such as deep brain stimulation (DBS), levodopa-carbidopa intestinal gel infusion (LCIG), and subcutaneous infusion of apomorphine, for managing advanced Parkinson's disease (PD). It's like a camel caravan exploring different strategies for navigating a desert landscape where motor fluctuations and dyskinesia pose significant challenges. The study found that all three therapies can effectively reduce off time and dyskinesia, improving quality of life for patients with advanced PD.

Finding the Right Path Through the Desert

The study highlights the effectiveness of device-aided therapies in managing advanced PD symptoms, offering hope for improved quality of life. It's like finding a network of oases that provide relief and support for those traversing a challenging desert landscape.

A Camel's Guide to Managing Parkinson's Disease

This research underscores the importance of exploring various treatment options for managing advanced PD. It's like a camel seeking out the most suitable route for a long desert journey – finding the right path can significantly impact the journey's outcome.

Dr. Camel's Conclusion

This study provides valuable insights into the use of device-aided therapies for managing advanced PD, offering hope for improved quality of life and greater control over symptoms. It's a reminder that even in the vast and challenging desert of neurodegenerative disease, there are oases of hope and innovation waiting to be explored.

Date :
  1. Date Completed 2018-03-19
  2. Date Revised 2018-03-26
Further Info :

Pubmed ID

28554418

DOI: Digital Object Identifier

10.1016/bs.irn.2017.03.001

Related Literature

Article Analysis
・Side Effects of levodopa and carbidopa
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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