Secukinumab is superior to fumaric acid esters in treating patients with moderate-to-severe plaque psoriasis who are naive to systemic treatments: results from the randomized controlled PRIME trial.

Author: AugustinM, HentschkeC, KneidlJ, MelzerN, MrowietzU, ReichK, SiederC, SticherlingM, ThaçiD

Paper Details 
Original Abstract of the Article :
BACKGROUND: Secukinumab is a fully human antibody that neutralizes interleukin-17A. It has significant efficacy and a favourable safety profile in moderate-to-severe plaque psoriasis and psoriatic arthritis. OBJECTIVES: To compare secukinumab with fumaric acid esters (FAEs) in a randomized controll...See full text at original site
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引用元:
https://doi.org/10.1111/bjd.15707

データ提供:米国国立医学図書館(NLM)

Secukinumab Takes the Lead in Psoriasis Treatment

Psoriasis, a chronic skin condition, can be a persistent and troublesome desert for those affected. This study compares the effectiveness of secukinumab, a targeted biologic treatment, to fumaric acid esters (FAEs), a traditional therapy, in treating moderate-to-severe plaque psoriasis. The study finds that secukinumab demonstrably outperforms FAEs in reducing psoriasis severity and improving patient quality of life. The results underscore the importance of personalized treatment approaches and the potential benefits of newer biologic therapies for psoriasis.

A New Era in Psoriasis Treatment: Navigating the Desert of Skin Disease

The study highlights a significant shift in the landscape of psoriasis treatment. Secukinumab's superior efficacy opens a new door for patients seeking effective and lasting relief from this challenging condition. This research underscores the power of targeted therapies and the importance of personalized medicine in improving patient outcomes.

Living with Psoriasis: Finding Your Own Oasis

The desert of psoriasis can be daunting, but the right treatment can help you find your own oasis of clear skin and improved quality of life. This study reminds us that progress in psoriasis treatment continues, offering hope for a brighter future for those living with this condition.

Dr. Camel's Conclusion

The desert of psoriasis can be a challenging place to navigate. This study offers a beacon of hope, highlighting the significant benefits of secukinumab, a new biologic therapy for psoriasis. With the right treatment and support, individuals with psoriasis can find their own oasis of relief and well-being.

Date :
  1. Date Completed 2018-06-18
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

28580646

DOI: Digital Object Identifier

10.1111/bjd.15707

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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