R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity.

Author: AherNilima Y, AherYogesh D, AradskaJana, Daba FeyissaDaniel, DragacevicVladimir, HoegerHarald, IlicMarija, KalabaPredrag, KorzVolker, LangerThierry, LubecGert, Saber MaroufBabak, ShanmugasundaramBharanidharan, SitteHarald H

Paper Details 
Original Abstract of the Article :
Modafinil is a wake promoting drug approved for clinical use and also has cognitive enhancing properties. Its enantiomer R-Modafinil (R-MO) is not well studied in regard to cognitive enhancing properties. Hence we studied its effect in a spatial memory paradigm and its possible effects on dentate gy...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482457/

データ提供:米国国立医学図書館(NLM)

R-Modafinil: Exploring the Oasis of Cognitive Enhancement

Modafinil, a wake-promoting drug known for its cognitive-enhancing properties, is like a desert oasis offering a boost of mental clarity. This research explores the cognitive enhancing effects of R-Modafinil, an enantiomer of modafinil, in a spatial memory paradigm. The researchers investigated the impact of R-Modafinil on spatial memory acquisition and dentate gyrus long-term potentiation (DG-LTP), a process crucial for memory formation. Their findings suggest that R-Modafinil, at clinically relevant doses, can enhance spatial memory performance and rescue DG-LTP from impairment, offering a potential for improving cognitive function.

R-Modafinil: A Potential Oasis for Cognitive Enhancement

The study provides valuable insights into the potential of R-Modafinil as a cognitive enhancer. The findings suggest that R-Modafinil could offer a promising tool for improving memory function and cognitive performance, particularly in individuals struggling with cognitive decline or those seeking to enhance their mental capabilities. However, it's important to note that further research is needed to confirm these findings and explore the long-term effects of R-Modafinil on cognitive function.

Navigating the Desert of Cognitive Decline

If you are concerned about cognitive decline or seeking ways to enhance your mental capabilities, consulting with a healthcare professional is essential. They can assess your individual needs and recommend the most appropriate approach, including potential benefits and risks of cognitive enhancers. Remember, there are ways to navigate the desert of cognitive decline and find tools to maintain or improve your mental function.

Dr.Camel's Conclusion

This research explores the potential of R-Modafinil as a cognitive enhancer, offering a glimpse into the oasis of enhanced memory and cognitive function. While more research is needed to confirm these findings and explore the long-term implications, the study provides valuable insights into the potential of R-Modafinil for improving cognitive performance. Remember, consulting with a healthcare professional is essential for exploring safe and effective strategies for managing cognitive function.

Date :
  1. Date Completed 2017-10-02
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28644892

DOI: Digital Object Identifier

PMC5482457

Related Literature

SNS
PICO Info
in preparation
Languages

English

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