Safety of the 2D/3D direct-acting antiviral regimen in HCV-induced Child-Pugh A cirrhosis - A pooled analysis.

Author: CohenDaniel E, CohenEric, FeldJordan J, FosterGraham R, FriedMichael W, LarsenLois, MobasheryNiloufar, NelsonDavid R, PoordadFred, TatschFernando, WedemeyerHeiner

Paper Details 
Original Abstract of the Article :
Chronic hepatitis C virus (HCV)-infected patients with cirrhosis are a high-priority population for treatment. To help inform the benefit-risk profile of the all-oral direct-acting antiviral (DAA) combination regimen of ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir (OBV/PTV/r±DS...See full text at original site
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引用元:
https://doi.org/10.1016/j.jhep.2017.06.011

データ提供:米国国立医学図書館(NLM)

Direct-Acting Antivirals: A Safe Option for Hepatitis C Cirrhosis?

This research explores the landscape of hepatology, examining the safety and efficacy of direct-acting antiviral (DAA) regimens, specifically the combination of ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir (OBV/PTV/r±DSV), for treating hepatitis C virus (HCV)-induced Child-Pugh A cirrhosis. It's like navigating a treacherous desert, where researchers seek to find safe and effective treatments for this challenging condition. The study, based on a comprehensive review of clinical trials, investigated the benefit-risk profile of these DAA regimens in patients with cirrhosis. It's as if the researchers, like seasoned explorers, meticulously analyzed the data, seeking to map the safest and most effective route through this challenging landscape.

DAA Regimens: A Potential Solution for Hepatitis C Cirrhosis

The study suggests that the OBV/PTV/r±DSV regimen may be a safe and effective treatment option for patients with Child-Pugh A cirrhosis. It's as if the researchers have discovered a hidden spring in the desert, offering a steady source of relief and hope for patients seeking to overcome this challenging condition.

A New Hope for Hepatitis C Patients

This research provides valuable information for clinicians treating patients with HCV-induced cirrhosis, offering a potentially safe and effective treatment option. It's as if this research has illuminated a path through the desert, guiding clinicians towards a more promising future for their patients.

Dr.Camel's Conclusion

This study sheds light on the potential of DAA regimens, like OBV/PTV/r±DSV, as a safe and effective treatment option for patients with hepatitis C cirrhosis. It's a beacon of hope in the desert of this challenging condition, offering a path towards a healthier future.

Date :
  1. Date Completed 2018-06-05
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

28645740

DOI: Digital Object Identifier

10.1016/j.jhep.2017.06.011

Related Literature

SNS
PICO Info
in preparation
Languages

English

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