Paper Details 
Original Abstract of the Article :
BACKGROUND: Fenoprofen calcium dehydrate (FCD) is counted as a non-steroidal, anti-inflammatory, anti-arthritic drug. FCD is slightly water soluble. It is indicated for mild pain relief, where the suggested dosage is 200 mg orally every 4 to 6 h. AIM: Reduce dissolution efficiency, reach an extende...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620564/

データ提供:米国国立医学図書館(NLM)

Fenoprofen Calcium Dihydrate: A Journey Through the Desert of Pain Relief

In the vast desert of pain relief, fenoprofen calcium dehydrate (FCD) stands as a beacon of hope, offering solace to those suffering from mild pain. This research delves into the world of drug delivery, exploring how polymers can enhance the therapeutic effectiveness of FCD, extending its reach and minimizing side effects.

The authors meticulously craft a journey through the desert of drug formulation, employing a combination of co-evaporated FCD-triacetyl-β-cyclodextrin complex and either hydroxylpropylmethyl cellulose (HPMC) or ethyl cellulose (EC) polymers. They discover that the EC/drug complex exhibits remarkable inhibition of inflammation and nociception, achieving a sustained effect due to a higher remaining amount after elapsing.

A New Oasis of Pain Management: Exploring Polymers and Drug Delivery

This research unveils a promising new oasis in the desert of pain management, where polymers play a crucial role in enhancing the therapeutic profile of FCD. The authors' findings suggest that these formulations could lead to more effective and longer-lasting pain relief, potentially minimizing the need for frequent medication.

Navigating the Desert of Side Effects: A Gentle Approach to Pain Relief

This study reminds us that even in the desert of pain management, where effective treatments are highly sought, it's crucial to prioritize safety. The authors' exploration of polymer-based formulations suggests a potential path towards gentler and more tolerable approaches to pain relief.

Dr. Camel's Conclusion

The authors' journey through the desert of drug formulation offers a valuable lesson: combining scientific ingenuity with a focus on patient well-being can lead to breakthroughs in pain management. Their research on EC/drug complex highlights the potential of polymers to transform the therapeutic landscape, offering a new oasis of hope in the desert of pain.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

28671624

DOI: Digital Object Identifier

PMC5620564

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.