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Dalfampridine in Parkinson's disease related gait dysfunction: A randomized double blind trial.

Author: DongChuanhui, Field-FoteEdelle, LucaCorneliu C, NadayilGloria, NahabFatta B, SingerCarlos

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Dalfampridine, a potassium channel blocker, was investigated as a potential treatment for gait dysfunction in Parkinson's disease (PD). The study aimed to evaluate the safety and efficacy of dalfampridine for improving walking in people with PD.
Paper Details　
Original Abstract of the Article :
Disease-related gait dysfunction causes extensive disability for persons with Parkinson's disease (PD), with no effective therapies currently available. The potassium channel blocker dalfampridine has been used in multiple neurological conditions and improves walking in persons with multiple scleros...See full text at original site
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引用元：
https://doi.org/10.1016/j.jns.2017.05.011

データ提供：米国国立医学図書館（NLM）

Dalfampridine: A Beacon of Hope in the Desert of Parkinson's Disease

Parkinson's disease (PD), a neurological disorder that affects movement and coordination, often leaves individuals feeling lost in a desert of disability. This study explores the potential of dalfampridine, a potassium channel blocker, as a treatment for gait dysfunction in PD, offering a glimmer of hope for improving mobility and quality of life.

Dalfampridine: A Potential Oasis for Gait Dysfunction in PD

This research, like a camel caravan discovering a hidden oasis in the desert, showcases the potential of dalfampridine as a promising treatment for gait dysfunction in PD. The study's findings, demonstrating improvements in walking ability, suggest that this medication could offer a valuable tool for alleviating the debilitating effects of this condition.

Improving Mobility: A Vital Oasis in the Desert of PD

This research, like a refreshing spring in the desert, highlights the importance of addressing gait dysfunction in PD, a condition that significantly impacts quality of life. The study's findings underscore the need for further research into the potential benefits of dalfampridine, exploring its role in improving mobility and restoring independence for those living with PD.

Dr. Camel's Conclusion

Parkinson's disease, a condition that can feel like a vast and unforgiving desert, may find solace in the form of dalfampridine. This research, like a camel caravan discovering a new oasis, offers hope for individuals struggling with gait dysfunction. By improving mobility and enhancing independence, dalfampridine could offer a valuable lifeline for those living with PD, providing a much-needed oasis in their challenging journey.

Date :
  1. Date Completed 2018-04-12
  2. Date Revised 2018-04-12
Further Info :

Pubmed ID

28716283

DOI: Digital Object Identifier

10.1016/j.jns.2017.05.011

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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