Effects of liver-stage clearance by Primaquine on gametocyte carriage of Plasmodium vivax and P. falciparum.

Author: BetuelaInoni, FelgerIngrid, HofmannNatalie E, KarlStephan, KinboroBenson, LorryLina, MuellerIvo, RobinsonLeanne J, SilkeyMariabeth, WampflerRahel

Paper Details 
Original Abstract of the Article :
Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-to-reinfection cohort in Papua New Guinean children per...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540608/

データ提供:米国国立医学図書館(NLM)

Primaquine: A Powerful Tool to Fight Malaria Transmission

This study delves into the important role of primaquine (PQ) in preventing malaria transmission. PQ is the only currently available antimalarial that can prevent relapses of *Plasmodium vivax* (Pv), a type of malaria parasite. The study investigates the effects of PQ treatment on the carriage of gametocytes, the sexually mature forms of malaria parasites that are responsible for transmitting the disease to mosquitoes. This research is like a journey through the desert of malaria prevention, uncovering the crucial role of PQ in reducing the spread of this debilitating disease.

Primaquine's Impact on Malaria Transmission: A Vital Weapon

The study found that PQ treatment effectively cleared mature gametocytes of both *P. vivax* and *P. falciparum*, reducing the potential for transmission to mosquitoes. This is like building a strong wall in the desert to block the spread of malaria, protecting communities from the threat of this deadly disease.

Malaria Prevention: A Collective Effort

This research highlights the importance of using effective antimalarial treatments, like PQ, to control malaria transmission. It's like a collective effort to build a network of oases in the desert of malaria prevention, providing safe havens for communities and ultimately reducing the burden of this disease.

Dr.Camel's Conclusion

This study underscores the importance of using PQ to prevent malaria transmission, offering a valuable tool in our fight against this devastating disease. It's like a beacon of hope in the desert of malaria prevention, guiding us towards a future where malaria is no longer a threat to human health.

Date :
  1. Date Completed 2017-08-10
  2. Date Revised 2020-12-14
Further Info :

Pubmed ID

28732068

DOI: Digital Object Identifier

PMC5540608

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Languages

English

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