Long-Term Antitumor Activity and Safety of Enzalutamide Monotherapy in Hormone Naïve Prostate Cancer: 3-Year Open Label Followup Results.

Author: BaronBenoit, BorreMichael, BraeckmanJohan, HeidenreichAxel, HeracekJiri, HirmandMohammad, IversenPeter, KrivoshikAndrew, RathenborgPer, SmithMatthew R, TombalBertrand, Van PoppelHendrik, WerbrouckPatrick

Paper Details 
Original Abstract of the Article :
A phase 2 study of enzalutamide monotherapy in patients with hormone naïve prostate cancer demonstrated high prostate specific antigen response rates at 25 weeks, 1 year and 2 years with minimal effects on total body bone mineral density and favorable safety. In this followup analysis we evaluated e...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.juro.2017.08.103

データ提供:米国国立医学図書館(NLM)

Enzalutamide: A Potential Oasis in the Desert of Prostate Cancer

The field of prostate cancer treatment is a complex and constantly evolving landscape, with researchers seeking to develop new and effective therapies to combat this prevalent disease. This study explores the long-term efficacy and safety of enzalutamide, a novel androgen receptor inhibitor, in patients with hormone-naive prostate cancer. The authors meticulously examine the results of a phase 2 study, highlighting enzalutamide's potential as a safe and effective treatment option, demonstrating its ability to suppress tumor growth and maintain bone health over an extended period.

Enzalutamide: A Beacon of Hope in the Desert of Prostate Cancer

The study's findings offer compelling evidence for the potential of enzalutamide as a promising treatment for hormone-naive prostate cancer. Its ability to suppress tumor growth and maintain bone health over a prolonged period provides a glimmer of hope for patients facing this challenging disease. These findings, like a refreshing oasis in the desert of prostate cancer, offer a new avenue for treatment and potentially improved outcomes for those affected.

Finding Hope: Navigating the Desert of Prostate Cancer

This research underscores the importance of continued research and development of new therapies for prostate cancer. By understanding the mechanisms behind enzalutamide's efficacy and safety, researchers can refine treatment strategies and potentially improve long-term outcomes for patients. Just as a camel adapts to the challenges of the desert environment, we must continue to evolve our approaches to treating prostate cancer, offering individuals a more effective path towards a healthier future.

Dr.Camel's Conclusion

This study provides a beacon of hope in the often-treacherous desert of prostate cancer. Enzalutamide, with its demonstrated efficacy and safety profile, offers a potential oasis for patients seeking effective and long-lasting treatment. It's a reminder that even in the face of challenging health conditions, there is always room for progress and the potential for finding new solutions.

Date :
  1. Date Completed 2019-04-03
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

28867562

DOI: Digital Object Identifier

10.1016/j.juro.2017.08.103

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.