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Drug-induced immune hemolytic anemia associated with anti-vancomycin complicated by a paraben antibody.

Author: ArndtPatricia A, ChengEdward Y, GniadekThomas J, LegerRegina M, ZantekNicole D, ZydowiczDaniel

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

Drug-induced immune hemolytic anemia (DIIHA) is rare but potentially life-threatening. Diagnosis requires high clinical suspicion due to the expanding list of medications that can induce DIIHA. In vitro antibody reactivity against reagent additives may complicate test interpretation.
Paper Details　
Original Abstract of the Article :
Drug-induced immune hemolytic anemia (DIIHA) is rare, but potentially life-threatening. A high index of clinical suspicion is required for diagnosis, since the number of medications known to induce DIIHA continues to expand. Additionally, in vitro antibody reactivity against reagent additives has be...See full text at original site
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引用元：
https://doi.org/10.1111/trf.14362

データ提供：米国国立医学図書館（NLM）

Drug-Induced Immune Hemolytic Anemia: A Complicated Case

The field of hematology is a vast desert, often encountering the challenges of diagnosing and treating rare and complex blood disorders. This case report focuses on drug-induced immune hemolytic anemia (DIIHA), a potentially life-threatening condition that can be challenging to diagnose. The researchers describe a complex case of DIIHA associated with anti-vancomycin antibodies, further complicated by the presence of a paraben antibody. This report highlights the importance of a high index of clinical suspicion for DIIHA, emphasizing the need for careful evaluation of medication history and potential drug-related immune reactions.

A Complex Case Underscores the Need for Careful Diagnosis

This case report highlights the complex nature of DIIHA, emphasizing the need for a high index of clinical suspicion for this potentially life-threatening condition. The researchers' experience underscores the importance of considering the role of drug-related immune reactions in the development of anemia. This case report serves as a valuable reminder for healthcare providers to remain vigilant in identifying and managing DIIHA.

Navigating the Challenges of Diagnosing DIIHA

This case report provides a valuable glimpse into the challenges associated with diagnosing and managing DIIHA. The researchers' experience highlights the importance of careful evaluation of medication history and potential drug-related immune reactions. This case report is a reminder that the desert of hematology often presents complex and challenging cases, requiring a high index of clinical suspicion and a thorough understanding of the nuances of blood disorders.

Dr.Camel's Conclusion

This case report underscores the importance of careful diagnosis and management of DIIHA, a potentially life-threatening condition. The researchers' experience highlights the complex nature of this condition and the need for a high index of clinical suspicion for drug-related immune reactions. This study is a reminder that the desert of hematology often presents complex and challenging cases, requiring a thorough understanding of the nuances of blood disorders.

Date :
  1. Date Completed 2018-09-10
  2. Date Revised 2018-09-10
Further Info :

Pubmed ID

28990203

DOI: Digital Object Identifier

10.1111/trf.14362

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Languages

English

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