Therapeutic Efficacy of Methazolamide Against Intermittent Hypoxia-Induced Excessive Erythrocytosis in Rats.

Author: ChenZhaoli, DengBingnan, DuanRuifeng, LiXi, LiuWei, LiuXiaohua, NieHongjing, XiaoZhonghai, YangDanfeng, ZhangZhiqing

Paper Details 
Original Abstract of the Article :
Zhang, Zhiqing, Zhonghai Xiao, Bingnan Deng, Xiaohua Liu, Wei Liu, Hongjing Nie, Xi Li, Zhaoli Chen, Danfeng Yang, and Ruifeng Duan. Therapeutic efficacy of methazolamide against intermittent hypoxia-induced excessive erythrocytosis in rats. High Alt Med Biol 19:69-80, 2018.-This study aimed to dete...See full text at original site
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引用元:
https://doi.org/10.1089/ham.2017.0044

データ提供:米国国立医学図書館(NLM)

Methazolamide: A Potential Treatment for Excessive Erythrocytosis

This research investigates the therapeutic efficacy of methazolamide, a carbonic anhydrase inhibitor, in treating excessive erythrocytosis, a condition characterized by an abnormally high number of red blood cells. The study, conducted in rats exposed to intermittent hypoxia, evaluated the effects of different doses of methazolamide on various hematological, hemorheological, and biochemical parameters. The researchers found that methazolamide effectively reduced hemoglobin concentration, hematocrit, and blood viscosity in a dose-dependent manner, demonstrating its potential as a therapeutic agent for excessive erythrocytosis.

Methazolamide: A Promising Treatment for Excessive Erythrocytosis

This study demonstrates the potential of methazolamide as a treatment for excessive erythrocytosis. The researchers observed a dose-dependent reduction in hemoglobin concentration, hematocrit, and blood viscosity, indicating the effectiveness of methazolamide in managing this condition. The study's findings suggest that methazolamide could offer a valuable therapeutic option for patients with excessive erythrocytosis.

Managing Excessive Erythrocytosis: A Step Towards Better Health

This research highlights the importance of exploring novel therapeutic options for managing excessive erythrocytosis. The study's findings on the effectiveness of methazolamide suggest a promising avenue for improving the health of individuals suffering from this condition. Further research is needed to fully understand the long-term effects and safety of methazolamide in humans, but the study offers hope for a more effective and targeted treatment for excessive erythrocytosis.

Dr.Camel's Conclusion

Just as a camel navigates the desert with an adaptive body and a thirst for water, we must explore innovative solutions for managing complex health conditions. This research sheds light on the potential of methazolamide as a therapeutic agent for excessive erythrocytosis. The study's findings offer hope for a more effective and targeted treatment for this condition, potentially improving the lives of many individuals. Let's continue our journey through the desert of medical research, seeking new pathways to better health and well-being.

Date :
  1. Date Completed 2018-12-21
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

29077517

DOI: Digital Object Identifier

10.1089/ham.2017.0044

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SNS
PICO Info
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Languages

English

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