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Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people: systematic review and economic evaluation.

Author: DuarteAna, GoncalvesPedro Saramago, HardenMelissa, MebrahtuTeumzghi, MurphyRuth, PalmerStephen, RodgersMark, RotheryClaire, WoolacottNerys

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study discusses the biological treatments (adalimumab, etanercept, and ustekinumab) licensed for psoriasis in children, acknowledging the need for further research on their long-term safety and efficacy.
Paper Details　
Original Abstract of the Article :
Label="BACKGROUND">Psoriasis is a chronic inflammatory disease that predominantly affects the skin. Adalimumab (HUMIRA<sup>&#174;</sup>, AbbVie, Maidenhead, UK), etanercept (Enbrel<sup>&#174;</sup>, Pfizer, New York, NY, USA) and ustekinumab (STELARA<sup>&#174;</sup>, Janssen Biotech, Inc., Titusvil...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694897/

データ提供：米国国立医学図書館（NLM）

Biologics for Psoriasis: A Desert Oasis for Children

Psoriasis, a chronic skin condition that can cause itchy, scaly patches, can be a daunting challenge for children. This research explores the use of biologics, medications that target specific parts of the immune system, as a potential treatment for psoriasis in children, offering a pathway to a clearer, smoother skin landscape.

Finding a Path to Clearer Skin

The researchers meticulously reviewed studies on the effectiveness of three biologics (adalimumab, etanercept, and ustekinumab) in treating psoriasis in children. They found that these medications can be effective in controlling psoriasis symptoms, offering a glimmer of hope for children struggling with this condition.

A New Dawn for Psoriasis Treatment

This research provides valuable insights into the use of biologics for pediatric psoriasis. It highlights the importance of individualized treatment approaches and the need for further research to optimize the use of these medications in children.

Dr.Camel's Conclusion

This study, like a desert oasis, offers a beacon of hope for children battling psoriasis. It reminds us that with ongoing research and innovative treatments, we can provide children with the tools they need to navigate the challenges of psoriasis and achieve a better quality of life.

Date :
  1. Date Completed 2018-07-25
  2. Date Revised 2021-04-21
Further Info :

Pubmed ID

29105621

DOI: Digital Object Identifier

PMC5694897

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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