Neuroocular side effects of carbamazepine and phenobarbital in epileptic patients as measured by saccadic eye movements analysis.

Author: AlloccaS, BaruzziA, BonavitaV, CasucciG, Di CostanzoA, QuattroneA, RivaR, TataM R, TedeschiG

Paper Details 
Original Abstract of the Article :
The effect of carbamazepine (CBZ) and phenobarbital (PB), alone and in association, on the function of specific brain structures was studied in chronically treated epileptic patients by means of saccadic eye movements (SEMs) analysis. The relationship between daily fluctuations of CBZ plasma levels ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/j.1528-1157.1989.tb05282.x

データ提供:米国国立医学図書館(NLM)

Navigating the Brain's Desert: The Effects of Antiepileptic Drugs on Eye Movements

The human brain, like a vast and intricate desert, harbors complex neurological pathways. This research delves into the effects of carbamazepine (CBZ) and phenobarbital (PB), two commonly prescribed antiepileptic drugs, on saccadic eye movements, a key indicator of brain function. The authors, like intrepid explorers traversing the desert of neurological disorders, aim to shed light on the impact of these medications on specific brain structures.

Antiepileptic Drugs: A Double-Edged Sword

This study, like a desert mirage, unveils the complex effects of antiepileptic drugs on brain function. Both CBZ and PB were found to impair saccadic eye movements, suggesting potential neurological side effects. However, the authors emphasize that these impairments may not reach clinical significance, highlighting the importance of careful monitoring and management. The study further reveals that PB has a more pronounced sedative effect compared to CBZ, offering valuable insights for clinicians when prescribing these medications.

Managing the Side Effects of Antiepileptic Drugs

The findings of this study serve as a reminder that even seemingly benign treatments can have unintended consequences. The authors emphasize the importance of monitoring patients for potential side effects, especially when using antiepileptic drugs. This research, like a guidebook for navigating the desert of neurological conditions, provides valuable information for clinicians to optimize treatment strategies and minimize potential risks.

Dr.Camel's Conclusion

This research, like a map revealing hidden pathways in the vast desert of the human brain, provides valuable insights into the complex effects of antiepileptic drugs on brain function. The authors, like astute desert guides, highlight the potential side effects of these medications, emphasizing the importance of careful monitoring and management. This study serves as a reminder that even in the quest for treatment, we must remain vigilant in navigating the complexities of the human body.

Date :
  1. Date Completed 1989-03-01
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

2912718

DOI: Digital Object Identifier

10.1111/j.1528-1157.1989.tb05282.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.