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Effect of Single Intra-cutaneous Injection for Acute Thoracic Herpes Zoster and Incidence of Postherpetic Neuralgia.

Author: CuiJi-Zheng, GengZhu-Sheng, WangXin-Ling, YanFang, YangXiao-Na, ZhangJin-Wei, ZhangXiao-Bao, ZhaoZhi-Bin

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the effect of a single intra-cutaneous injection of ropivacaine plus methylprednisolone on acute thoracic herpes zoster (HZ) pain intensity and duration, eruptive duration, and PHN incidence. The active group displayed a significantly shorter duration of pain and herpetic eruption than the placebo group. A significantly lower incidence of PHN was encountered in the active group after 4 weeks and 12 weeks.
Paper Details　
Original Abstract of the Article :
The therapeutic effect of postherpetic neuralgia (PHN) is often disappointing and challenging. The role of intra-cutaneous injection of local anesthetic and steroids in preventing PHN remains unknown. The purpose of this study was to investigate the effect of a single intra-cutaneous injection of ro...See full text at original site
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引用元：
https://doi.org/10.1016/j.pmn.2017.09.002

データ提供：米国国立医学図書館（NLM）

A New Oasis in the Desert of Herpes Zoster: Reducing the Risk of Postherpetic Neuralgia

Herpes zoster, commonly known as shingles, can leave individuals with lingering pain, a harsh desert they must navigate. This study investigates the potential benefits of a single intra-cutaneous injection of ropivacaine plus methylprednisolone in reducing the incidence of postherpetic neuralgia (PHN), a debilitating complication of herpes zoster. The authors aim to identify a new approach for preventing PHN, alleviating the long-term pain and discomfort associated with this condition.

Finding Relief in the Desert: Reducing the Risk of Postherpetic Neuralgia

The study demonstrates that the single intra-cutaneous injection of ropivacaine plus methylprednisolone significantly reduces the incidence of PHN, potentially offering a new way to manage this challenging condition. The study participants who received the injection experienced a significantly shorter duration of pain and herpetic eruption, suggesting that this approach may also reduce the overall severity of the herpes zoster infection.

Navigating the Desert of Herpes Zoster: Preventing Long-Term Pain

This study highlights the importance of early intervention in managing herpes zoster, seeking to prevent the development of debilitating complications like PHN. The study's findings suggest that a single intra-cutaneous injection of ropivacaine plus methylprednisolone may offer a valuable tool for reducing the risk of PHN, potentially alleviating the long-term pain and discomfort associated with this condition.

Dr. Camel's Conclusion

This study provides a glimmer of hope in the desert of herpes zoster, demonstrating that a single intra-cutaneous injection can significantly reduce the risk of developing PHN. This finding offers a potentially valuable tool for clinicians seeking to prevent long-term pain and discomfort for their patients. The study's emphasis on early intervention highlights the importance of timely diagnosis and treatment for herpes zoster, minimizing the chances of developing complications and improving patient outcomes.

Date :
  1. Date Completed 2018-10-01
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

29153295

DOI: Digital Object Identifier

10.1016/j.pmn.2017.09.002

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