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[Safety of SGLT2 inhibitors. A review of the adverse drug reactions registered in a national database].
Author: Esteban-JiménezO, Navarro-PemánC, Urieta-GonzálezL
Original Abstract of the Article :
OBJECTIVE: To analyse the adverse drug reactions (ADRs) caused by Sodium-glucose Cotransporter-2 Inhibitors (SGLT2i) notified in Spain since they have been on the market. MATERIAL AND METHODS: An analysis was made of all the notifications registered in the Spanish Pharmacovigilance System of drugs ...See full text at original site
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.semerg.2017.10.003
データ提供:米国国立医学図書館(NLM)
Navigating the Side Effects of SGLT2 Inhibitors: A Pharmacovigilance Study
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are a class of drugs used to manage type 2 diabetes. While effective in lowering blood sugar levels, SGLT2i can also cause side effects. This research analyzes adverse drug reactions (ADRs) reported to the Spanish Pharmacovigilance System related to the use of SGLT2i. The study found that the most common ADRs were urinary tract infections, diabetic ketoacidosis, and kidney damage. While most urinary tract infections were not serious, ketoacidosis and kidney damage posed significant risks, requiring hospitalization and sometimes even life-threatening interventions.
The Importance of Monitoring and Reporting ADRs
This research underscores the importance of pharmacovigilance systems for monitoring and reporting ADRs related to medications. The findings highlight the potential risks associated with SGLT2i and the need for careful monitoring of patients, particularly those with pre-existing kidney conditions.
Safeguarding Diabetes Management: A Balanced Approach
Managing diabetes is like navigating a desert oasis, with a delicate balance between maintaining blood sugar levels and managing potential risks. This research emphasizes the importance of a cautious approach to SGLT2i therapy, weighing the potential benefits against the risks and closely monitoring patients for any adverse effects.
Dr. Camel's Conclusion
The desert is a place of both beauty and danger, and managing diabetes can feel like navigating a similar landscape. This research helps us understand the potential risks associated with SGLT2i therapy, urging us to proceed with caution and monitor closely for any adverse effects. It's a reminder that even in the pursuit of wellness, we must be vigilant and mindful of the potential pitfalls along the way.
Date :
- Date Completed 2018-09-05
- Date Revised 2019-12-10
Further Info :
Related Literature
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