Paper Details
- Home
- Paper Details
Brain Targeted Intranasal Zaleplon Nano-emulsion: In-Vitro Characterization and Assessment of Gamma Aminobutyric Acid Levels in Rabbits' Brain and Plasma at Low and High Doses.
Author: Abd-ElrasheedEman, El-AshmoonyManal M, El-HelalySara Nageeb, SalahSalwa
Original Abstract of the Article :
Zaleplon is a pyrazolopyrimidin derivative hypnotic drug indicated for the short-term management of insomnia. Zaleplon belongs to Class II drugs, according to the biopharmaceutical classification system (BCS), showing poor solubility and high permeability. It undergoes extensive first-pass hepatic m...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://doi.org/10.2174/1567201814666171130121732
データ提供：米国国立医学図書館（NLM）
Brain Targeted Intranasal Zaleplon Nano-emulsion: A Novel Approach to Insomnia Treatment
Insomnia, the persistent inability to fall asleep or stay asleep, can have a profound impact on quality of life. This research explores a novel approach to insomnia treatment using intranasal delivery of zaleplon, a hypnotic medication. The authors developed a nano-emulsion formulation of zaleplon that is specifically designed for brain targeting, aiming to improve efficacy and reduce side effects. Their findings suggest that this new formulation holds promise for treating insomnia, offering a potential alternative to traditional oral medications.
Beyond the Pill: A New Frontier in Insomnia Treatment
This research challenges the traditional approach to insomnia treatment, exploring the potential of intranasal delivery of zaleplon. The study's findings suggest that this novel approach could offer a more effective and potentially safer alternative to oral medications, addressing the limitations of existing therapies. The development of targeted therapies for insomnia represents a significant advancement in the field of sleep medicine.
Delivering Relief: Targeted Therapy for Insomnia
The development of a brain-targeted nano-emulsion formulation of zaleplon represents a significant step forward in the treatment of insomnia. This targeted approach aims to deliver the medication directly to the brain, potentially improving efficacy and reducing side effects. The study's findings offer hope for individuals struggling with insomnia, suggesting that new and innovative treatment options are on the horizon.
Dr.Camel's Conclusion
Just as a desert traveler seeks a cool oasis in the scorching heat, individuals struggling with insomnia yearn for a restful night's sleep. This research offers a glimpse into a new frontier in insomnia treatment, exploring the potential of targeted drug delivery to provide much-needed relief.
Date :
- Date Completed 2018-12-12
- Date Revised 2018-12-12
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.