Effectiveness of various hip preservation treatments for non-traumatic osteonecrosis of the femoral head: A network meta-analysis of randomized controlled trials.

Author: ChenXianjun, PangQingjiang, ShiLin, YangJi, YuXiao, ZhangDifeng

Paper Details 
Original Abstract of the Article :
BACKGROUND: Non-traumatic osteonecrosis of the femoral head (ONFH) is a refractory osteonecrosis disease caused by an abnormal blood supply to bone tissue. However, therapeutic hip preservation strategies are diverse, and the therapeutic outcomes are not ideal. OBJECTIVE: A network meta-analysis wa...See full text at original site
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引用元:
https://doi.org/10.1016/j.jos.2017.12.004

データ提供:米国国立医学図書館(NLM)

Hip Preservation: A Network Meta-Analysis

The study delves into the complex world of [Orthopedics] by meticulously analyzing the effectiveness of various hip preservation treatments for non-traumatic osteonecrosis of the femoral head (ONFH). This condition, often referred to as ‘avascular necrosis,’ occurs when the bone tissue fails to receive adequate blood supply, leading to potential collapse and debilitating pain. This research, like a patient, meticulously undergoes a network meta-analysis to compare the relative effectiveness of different therapeutic approaches. The authors meticulously dissect the data, comparing treatments such as core decompression (CD) plus cytotherapy, alendronate treatment, extracorporeal shock wave therapy (ESWT) plus alendronate, and avascular biomaterials plus cytotherapy. This comprehensive analysis unveils the relative superiority of CD plus cytotherapy in reducing treatment failure rates, while ESWT emerged as the most effective treatment for improving Harris hip scores.

CD Plus Cytotherapy: A Promising Path

The findings reveal that CD plus cytotherapy is a more effective treatment for reducing treatment failure rates in early and intermediate stages of ONFH. The research suggests that this combination offers a promising path towards improved outcomes for patients struggling with this condition.

Hip Health Matters

The hip is a critical component of our musculoskeletal system. This research underscores the importance of seeking prompt diagnosis and appropriate treatment for ONFH. Early intervention can help preserve hip function and improve long-term quality of life.

Dr. Camel's Conclusion

This research sheds light on the complex landscape of ONFH treatment options, providing valuable insights into the relative effectiveness of various approaches. The study is akin to a desert oasis, offering hope and a path toward improved outcomes for patients grappling with this challenging condition. The findings suggest that CD plus cytotherapy may hold the key to a more effective treatment strategy.

Date :
  1. Date Completed 2018-10-01
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

29291916

DOI: Digital Object Identifier

10.1016/j.jos.2017.12.004

Related Literature

SNS
PICO Info
in preparation
Languages

English

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