Paper Details

  1. Home
  2. Paper Details

First-week clinical responses to dexlansoprazole 60 mg and esomeprazole 40 mg for the treatment of grades A and B gastroesophageal reflux disease.

Author: , ChuahSeng-Kee, HsuPin-I, HuangChih-Fang, KuoChao-Hung, KuoMing-Te, LiangChih-Ming, TaiWei-Chen, TsaiCheng-En, WangHsing-Ming, WangJiunn-Wei, WangYao-Kuang, WuDeng-Chyang, WuKeng-Liang, YangShih-Cheng, YaoChih-Chien

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The study found that the overall CSR for GERD patients was similar at days 1-7 for both the dexlansoprazole and esomeprazole groups, although a higher incidence of CSR was observed on day 3 in female patients who received a single dose of dexlansoprazole.
Paper Details　
Original Abstract of the Article :
AIM: To compare the one-week clinical effects of single doses of dexlansoprazole and esomeprazole on grades A and B erosive esophagitis. METHODS: We enrolled 175 adult patients with gastroesophageal reflux disease (GERD). The patients were randomized in a 1:1 ratio into two sequence groups to defin...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743510/

データ提供：米国国立医学図書館（NLM）

Dexlansoprazole vs. Esomeprazole: Comparing First-Week Effects in GERD

In the vast and complex landscape of [gastrointestinal disorders], [gastroesophageal reflux disease (GERD)] remains a common and often challenging condition. This study delves into the comparative efficacy of two commonly prescribed [proton pump inhibitors] (PPIs), [dexlansoprazole] and [esomeprazole], in managing the symptoms of [GERD]. This study aims to evaluate the short-term clinical effects of these medications on [grades A and B erosive esophagitis] in patients with [GERD].

Dexlansoprazole Shows Promise in the First Week of GERD Treatment

The research indicated that both [dexlansoprazole] and [esomeprazole] demonstrated comparable short-term clinical responses in patients with [GERD]. However, the study highlighted a slightly more rapid response to [dexlansoprazole] in female patients, suggesting potential gender-specific differences in [PPI] effectiveness. These findings contribute to the ongoing understanding of the nuances of [GERD] management.

Navigating GERD Treatment Options: Consider Personalized Approach

This research, like a well-stocked desert oasis, provides valuable insights into the [treatment landscape] for [GERD]. The findings highlight the potential for [personalized approaches] to [GERD] management, taking into account factors such as [gender] and individual responses to specific [PPIs]. This study underscores the importance of continued research in understanding the complexities of [GERD] and optimizing [treatment strategies].

Dr. Camel's Conclusion

This research, like a map guiding us through the desert of [GERD], sheds light on the effectiveness of two commonly prescribed [PPIs]. The study highlights the need for a nuanced and personalized approach to [GERD] management, taking into account factors such as [gender] and individual responses to medications. This is a reminder that there's no one-size-fits-all solution to [GERD], and that ongoing research is essential for optimizing [treatment outcomes].

Date :
  1. Date Completed 2018-08-08
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

29307999

DOI: Digital Object Identifier

PMC5743510

Related Literature

Article Analysis
・Effects of dexlansoprazole
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.