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Is selective 5-HT<sub>1F</sub> receptor agonism an entity apart from that of the triptans in antimigraine therapy?
Author: Labastida-RamírezAlejandro, MaassenVanDenBrinkAntoinette, Rubio-BeltránEloísa, VillalónCarlos M
Original Abstract of the Article :
Migraine is a neurovascular disorder that involves activation of the trigeminovascular system and cranial vasodilation mediated by release of calcitonin gene-related peptide (CGRP). The gold standard for acute migraine treatment are the triptans, 5-HT<sub>1B/1D/(1F)</sub> receptor agonists. Their ac...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.pharmthera.2018.01.005
データ提供:米国国立医学図書館(NLM)
Ditans: A New Era for Migraine Treatment?
This review explores the potential of ditans, or selective 5-HT1F receptor agonists, as a novel treatment for migraine. It compares and contrasts ditans with triptans, the current gold standard for acute migraine treatment. The authors focus on the specific action of ditans on the [trigeminovascular system] and their [cardiovascular safety] profile.Ditans: Navigating the Complexities of Migraine Treatment
This research delves into the [fascinating world] of [migraine treatment] and explores the potential of ditans as a new therapeutic approach. The authors highlight the [unique characteristics] of ditans, such as their selectivity for the 5-HT1F receptor and their [favorable cardiovascular profile]. Ditans might offer a safer and more effective treatment option for migraine sufferers, particularly those with cardiovascular concerns.Addressing the [Individualized Needs] of Migraine Sufferers
Migraine is a complex condition, and finding the [right treatment] can be a journey. This research sheds light on the [potential] of ditans, a new class of migraine medications, to offer a [more targeted approach] to treatment. By understanding the specific actions of ditans and their potential benefits, individuals can work with their healthcare providers to [make informed decisions] about their migraine management.Dr. Camel's Conclusion
The search for effective and safe migraine treatments continues. This review highlights the [promise] of ditans, selective 5-HT1F receptor agonists. Ditans may offer a new way to [tackle migraine] while minimizing the cardiovascular risks associated with traditional triptans. Just as a [camel's call] resonates across the vast desert, ditans could offer a [clearer path] for individuals seeking relief from migraine symptoms.Date :
- Date Completed 2019-02-04
- Date Revised 2023-12-13
Further Info :
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English
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