Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: II: Maternal risks.

Author: , AmatoMaria Pia, AnnovazziPietro, Brescia MorraVincenzo, CavallaPaola, CoccoEleonora, ComiGiancarlo, De GiglioLaura, GalloPaolo, GhezziAngelo, GianniniMarta, LanzilloRoberta, LaroniAlice, MarrosuMaria Giovanna, MartinelliVittorio, MoiolaLucia, PaolicelliDamiano, PastòLuisa, PortaccioEmilio, PozzilliCarlo, RinaldiFrancesca, SolaroClaudio, TortorellaCarla, TrojanoMaria, UccelliAntonio, ZaffaroniMauro

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To assess the risk of disease reactivation during pregnancy after natalizumab suspension in women with multiple sclerosis (MS). METHODS: Data of all pregnancies occurring between 2009 and 2015 in patients with MS treated with natalizumab and referring to 19 participating sites were colle...See full text at original site
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引用元:
https://doi.org/10.1212/WNL.0000000000005068

データ提供:米国国立医学図書館(NLM)

Navigating Pregnancy and Multiple Sclerosis: A Journey Through the Sands of Uncertainty

Multiple sclerosis (MS) presents unique challenges for women considering pregnancy. This research examines the risks of disease reactivation during pregnancy for women treated with natalizumab, a medication used to manage MS. It's like navigating a treacherous desert landscape, carefully weighing the risks and benefits of different paths.

The study found that women who had been treated with natalizumab had a higher relapse rate during and after pregnancy compared to those treated with interferon-β or no treatment. This finding is like discovering a hidden danger in the desert, a potential hazard that needs to be carefully considered.

The study recommends a careful balance of avoiding natalizumab washout and resuming treatment after delivery to minimize risks. This is like finding a safe passage through a dangerous terrain, choosing a route that minimizes potential hazards while ensuring the well-being of both mother and child.

A Delicate Balance

This research highlights the complex interplay between MS treatment, pregnancy, and the potential risks of disease reactivation. It's like navigating a delicate balance in a desert ecosystem, where every decision has consequences. The study encourages careful consideration and open communication between patients and healthcare providers to optimize outcomes.

Supporting Women with MS

The study underscores the importance of providing comprehensive care and support for women with MS who are considering pregnancy. It's like offering a safe haven in a challenging desert, providing resources and guidance to ensure a healthy journey. This research encourages us to create a more supportive and understanding environment for women facing these complex medical decisions.

Dr.Camel's Conclusion

This research offers valuable insights for women with MS considering pregnancy. It highlights the complexities of managing MS treatment during pregnancy, underscoring the need for careful planning and informed decision-making. It's a reminder that even in the most challenging deserts, with careful navigation and supportive guidance, a healthy and fulfilling journey is possible.

Date :
  1. Date Completed 2019-07-24
  2. Date Revised 2019-07-24
Further Info :

Pubmed ID

29438041

DOI: Digital Object Identifier

10.1212/WNL.0000000000005068

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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