Effects of repeated potassium iodide administration on genes involved in synthesis and secretion of thyroid hormone in adult male rat.

Author: BenderitterMarc, DublineauIsabelle, EbrahimianTeni, GrisonStephane, JourdainJean-Rene, LebsirDalila, LestaevelPhilippe, ManensLine, PechAnnick, PhanGuillaume, SouidiMaâmar, SuhardDavid, TackKarine

Paper Details 
Original Abstract of the Article :
BACKGROUND: A single dose of potassium iodide (KI) is recommended to reduce the risk of thyroid cancer during nuclear accidents. However in case of prolonged radioiodine exposure, more than one dose of KI may be necessary. This work aims to evaluate the potential toxic effect of repeated administrat...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.mce.2018.02.017

データ提供:米国国立医学図書館(NLM)

Potassium Iodide and Thyroid Function: A Camel's Journey Through the Desert of Radiation

Radiation exposure, like a scorching sun in the desert, can pose significant threats to our health. This study examines the effects of repeated potassium iodide (KI) administration on thyroid function in rats. KI, like a resourceful camel, plays a vital role in protecting the thyroid gland from the damaging effects of radioactive iodine.

Navigating the Desert of Radiation: Understanding the Effects of Potassium Iodide

The study reveals that while repeated KI administration did not cause any significant changes in thyroid hormone levels, it did impact the expression of genes involved in thyroid hormone synthesis and secretion. This is like observing the camel's adaptation to the desert environment, altering its physiology to cope with the challenging conditions. This research provides valuable insights into the complex interplay between KI, thyroid function, and radiation exposure.

Protecting the Oasis: Strategies for Managing Radiation Exposure

This study underscores the importance of understanding the potential effects of KI on thyroid function, particularly in the context of prolonged radiation exposure. It's like knowing how to best utilize a camel's resources to navigate the desert safely and efficiently. This research provides valuable information for healthcare professionals and policymakers in developing effective strategies for managing radiation exposure and protecting thyroid health.

Dr. Camel's Conclusion

This research explores the complex relationship between potassium iodide, thyroid function, and radiation exposure. The study highlights the importance of further research to fully understand the long-term effects of repeated KI administration and to develop optimized strategies for managing radiation exposure. It's a reminder that the desert of radiation is a complex and challenging environment, and with careful planning and effective interventions, we can navigate its dangers and safeguard our health.

Date :
  1. Date Completed 2019-05-08
  2. Date Revised 2019-05-08
Further Info :

Pubmed ID

29496566

DOI: Digital Object Identifier

10.1016/j.mce.2018.02.017

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.