Management of hepatitis C viral infection in chronic kidney disease patients on hemodialysis in the era of direct-acting antivirals.

Author: ChoeWon Hyeok, KoSoon Young

Paper Details 
Original Abstract of the Article :
The advent of novel, direct-acting antiviral (DAA) regimens for hepatitis C viral (HCV) infection has revolutionized its treatment by producing a sustained virologic response of more than 95% with few side effects and no comorbidities in the general population. Until recently, ideal DAA regimens hav...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313022/

データ提供:米国国立医学図書館(NLM)

Treating Hepatitis C in Dialysis Patients: A New Frontier

The field of [Hepatitis C treatment] is constantly evolving, with the advent of [direct-acting antiviral (DAA) regimens] offering a beacon of hope for patients. These [DAA] regimens have transformed the landscape by achieving a sustained virologic response of over 95%, with minimal side effects. However, these advancements have not fully extended to patients with [severe renal impairment and end-stage renal disease], as research on their efficacy in this unique population is still emerging.

Dialysis Patients: A Unique Challenge

The challenge is even more pronounced in the context of [hemodialysis]. Identifying patients in need of treatment and preventing HCV transmission are critical considerations. However, recent studies have brought a ray of hope to this desert of uncertainty. Researchers have discovered that a combination of [paritaprevir/ ritonavir/ombitasvir and dasabuvir, elbasvir/grazoprevir, or glecaprevir/pibrentasir] successfully treats HCV infection in chronic kidney disease stage 4 or 5 patients with or without hemodialysis.

Promising Developments for a Vulnerable Population

This breakthrough offers a ray of hope for [chronic kidney disease stage 4 or 5 patients with or without hemodialysis]. These patients, who are often vulnerable to complications due to their condition, can now access effective treatment. The success of these DAA regimens in dialysis patients is a testament to the relentless pursuit of improved healthcare solutions.

Dr.Camel's Conclusion

As a researcher with a thirst for knowledge, I'm impressed by the progress made in understanding how to treat Hepatitis C in dialysis patients. These advancements are a testament to the dedication of medical professionals who are tirelessly working to improve the lives of patients facing unique challenges. The findings suggest that effective treatment options are becoming increasingly available for this vulnerable group, offering a glimmer of hope in a sometimes-difficult journey.

Date :
  1. Date Completed 2019-07-17
  2. Date Revised 2020-03-06
Further Info :

Pubmed ID

29544240

DOI: Digital Object Identifier

PMC6313022

Related Literature

SNS
PICO Info
in preparation
Languages

English

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