Fluoropyrimidine-induced cardiotoxicity.

Author: AgliettaMassimo, BonzanoAlessandro, CagnazzoCeleste, DepetrisIlaria, FilippiRoberto, LeoneFrancesco, MarinoDonatella

Paper Details 
Original Abstract of the Article :
Fluoropyrimidines (5-fluorouracil and capecitabine) are antimetabolite drugs, widely used for the treatment of a variety of cancers, both in adjuvant and in metastatic setting. Although the most common toxicities of these drugs have been extensively studied, robust data and comprehensive characteriz...See full text at original site
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引用元:
https://doi.org/10.1016/j.critrevonc.2018.02.002

データ提供:米国国立医学図書館(NLM)

Fluoropyrimidine-Induced Cardiotoxicity: Navigating a Desert of Potential Side Effects

Fluoropyrimidines, like powerful tools in a desert arsenal, are widely used in cancer treatment. This research delves into the potential side effects of these medications, specifically focusing on their impact on the heart. The authors, like vigilant desert explorers, have reviewed the available data on fluoropyrimidine-induced cardiotoxicity (FIC), a rare but potentially life-threatening condition. They highlight the importance of understanding the mechanisms of FIC, identifying risk factors, and developing effective diagnostic tools and treatment options.

Fluoropyrimidine-Induced Cardiotoxicity: A Hidden Oasis of Potential Risk

This study provides a comprehensive overview of FIC, highlighting the importance of careful monitoring and early detection. The authors emphasize the need for vigilance in managing patients receiving fluoropyrimidine-based therapies, recognizing that even seemingly minor signs of cardiac dysfunction can be a harbinger of serious complications.

Protecting the Heart in the Desert of Cancer Treatment: A Focus on Early Detection

The study highlights the importance of early detection and proactive management of FIC. By understanding the risk factors and potential complications, healthcare providers can implement strategies to minimize the risk of cardiac damage and ensure optimal treatment outcomes for patients receiving fluoropyrimidine-based therapies.

Dr. Camel's Conclusion

Fluoropyrimidine-induced cardiotoxicity is a reminder that even the most effective medications can have unintended consequences. This study, like a guide through a potentially treacherous desert, emphasizes the importance of vigilance, early detection, and comprehensive management strategies to ensure patient safety. By understanding the potential risks and implementing appropriate protocols, we can navigate the desert of cancer treatment with a greater sense of safety and confidence.

Date :
  1. Date Completed 2018-05-23
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

29548480

DOI: Digital Object Identifier

10.1016/j.critrevonc.2018.02.002

Related Literature

SNS
PICO Info
in preparation
Languages

English

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