Translational Biomarkers and Ex Vivo Models of Joint Tissues as a Tool for Drug Development in Rheumatoid Arthritis.

Author: Bay-JensenAnne-C, BraddockMartin, GantzelThorbjørn, GrahamEmma, JenkinsMartin A, KarsdalMorten A, Kjelgaard-PetersenCecilie F, MusaKishwar, PlattAdam, SlynnGillian, ThudiumChristian S, WeinblattMichael E

Paper Details 
Original Abstract of the Article :
Rheumatoid arthritis (RA) is a chronic and degenerative autoimmune joint disease that leads to disability, reduced quality of life, and increased mortality. Although several synthetic and biologic disease-modifying antirheumatic drugs are available, there is still a medical need for novel drugs that...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174937/

データ提供:米国国立医学図書館(NLM)

Translational Biomarkers and Ex Vivo Models: A New Oasis for Rheumatoid Arthritis Drug Development

This research explores the potential of translational biomarkers and ex vivo models in the development of new drugs for rheumatoid arthritis (RA). It's like discovering a new oasis in the vast and challenging desert of RA research, offering a source of hope for finding effective treatments. The researchers highlight the need for new drugs that control disease progression, as current treatment options often fall short. This is akin to navigating a treacherous desert landscape, where the search for effective therapies can be arduous. The study proposes the use of translational biomarkers and ex vivo models as tools to facilitate early decision-making in drug development. It's like finding a hidden spring of knowledge in the desert, providing valuable insights to guide the development of new and effective treatments.

Translational Biomarkers and Ex Vivo Models: A Beacon of Hope for RA Drug Development

The research suggests that translational biomarkers and ex vivo models could be valuable tools for predicting drug efficacy in RA, potentially leading to a faster and more efficient development process. It's like discovering a powerful compass in the desert of RA research, guiding the way towards more effective treatments. This research emphasizes the importance of utilizing these tools to identify promising drug candidates early in the development process, potentially reducing the number of failures in later stages of clinical trials. This is a significant step towards finding new and effective therapies for RA.

Navigating the Desert of Rheumatoid Arthritis

This research underscores the need for innovative approaches to drug development for rheumatoid arthritis. It's a reminder that even in the vast and challenging desert of this chronic condition, there can be hidden oases of hope and potential for healing. The study emphasizes the importance of incorporating translational biomarkers and ex vivo models into the drug development process, paving the way for faster and more efficient discovery of effective therapies. This is a testament to the power of research in transforming the landscape of disease treatment.

Dr.Camel's Conclusion

This research explores the potential of translational biomarkers and ex vivo models in accelerating the development of new drugs for rheumatoid arthritis (RA). It's like discovering a new oasis in the vast and challenging desert of RA research, offering a source of hope for finding effective treatments. The study's findings highlight the importance of utilizing these tools to guide drug development, potentially leading to faster and more efficient discovery of effective therapies. This is a testament to the power of research in transforming the landscape of disease treatment, offering a path towards a brighter future for those living with RA.

Date :
  1. Date Completed 2019-07-22
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

29669391

DOI: Digital Object Identifier

PMC6174937

Related Literature

SNS
PICO Info
in preparation
Languages

English

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