A pilot single arm observational study of sofosbuvir/ledipasvir (200 + 45 mg) in 6- to 12- year old children.

Author: AbdElgawadM M A H, El-KhayatH R, El-ShabrawiM H F, KamalE M, KamalN M, YakootM

Paper Details 
Original Abstract of the Article :
BACKGROUND: No available data on the use of sofosbuvir/ledipasvir combination in treatment of hepatitis C virus (HCV) infection in children 6- to 12- year old. AIM: To assess the safety and efficacy of sofosbuvir plus ledipasvir in children 6- to 12- year old with chronic HCV genotype 4 infection. ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/apt.14677

データ提供:米国国立医学図書館(NLM)

Sofosbuvir/Ledipasvir: A Promising Treatment for Hepatitis C in Children

The field of pediatrics is constantly searching for safe and effective treatments for chronic illnesses affecting children. This study investigates the efficacy and safety of sofosbuvir/ledipasvir, a combination therapy for hepatitis C virus (HCV) infection, in children aged 6-12 years. The researchers conducted a pilot observational study to assess the therapeutic potential of this medication in a young patient population.

Sofosbuvir/Ledipasvir Shows Promise in Treating Pediatric HCV Infection

The pilot study demonstrated that sofosbuvir/ledipasvir was safe and effective in treating chronic HCV genotype 4 infection in children aged 6-12 years. The medication achieved a high sustained virological response (SVR12) rate, indicating sustained viral suppression. These encouraging findings support the potential of sofosbuvir/ledipasvir as a valuable treatment option for pediatric HCV infection.

Hope for Pediatric Hepatitis C Treatment

This research offers a beacon of hope for children with hepatitis C, a chronic viral infection that can have significant long-term health implications. The study's findings suggest that sofosbuvir/ledipasvir could be a safe and effective treatment option for this patient population, potentially leading to improved outcomes and a brighter future for affected children. The study emphasizes the importance of continued research and clinical trials to further evaluate the efficacy and safety of this medication in pediatric HCV infection.

Dr. Camel's Conclusion

This research, like a gentle desert breeze bringing relief from the heat, offers a promising solution for children struggling with hepatitis C. The study demonstrates the potential of sofosbuvir/ledipasvir as a safe and effective treatment option for this patient population. This research, like a shimmering oasis in the vast desert of pediatric healthcare, points towards a future where innovative therapies can transform the lives of children affected by chronic illnesses.

Date :
  1. Date Completed 2019-09-16
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

29696674

DOI: Digital Object Identifier

10.1111/apt.14677

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.