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The Impact of Pazopanib on the Cardiovascular System.

Author: BaichTesla M, DerbalaMohamed H, GuoAaron S, HoThai H, JusticeCody N, KemptonAmber N, SmithSakima A

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review focuses on the mechanisms responsible for pazopanib's toxicity to the cardiovascular system.
Paper Details　
Original Abstract of the Article :
Pazopanib is an approved treatment for renal cell carcinoma and a second-line treatment for nonadipocytic soft-tissue sarcoma. However, its clinical efficacy is limited by its cardiovascular side effects. Pazopanib and other vascular endothelial growth factor receptor tyrosine kinase inhibitors have...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/29706106

データ提供：米国国立医学図書館（NLM）

Pazopanib: A Double-Edged Sword in Cancer Treatment

This research delves into the realm of cancer treatment, a field as complex and ever-evolving as the shifting sands of a desert. The study focuses on pazopanib, a drug used to treat certain types of cancers, and explores its potential cardiovascular side effects. This research is crucial for understanding the potential risks and benefits of pazopanib, ensuring informed decision-making in cancer care.

Navigating the Risks and Benefits of Pazopanib

The researchers found that pazopanib, while effective in treating certain cancers, can be associated with cardiovascular side effects, including hypertension and QT interval prolongation. This study highlights the importance of carefully monitoring patients receiving pazopanib to minimize these risks.

Cancer Treatment: A Delicate Balance

This research underscores the delicate balance between the benefits and risks of cancer treatments, reminding us that the journey toward recovery is often complex and requires careful consideration of individual patient factors.

Dr.Camel's Conclusion

This research reminds us that the pursuit of a cure for cancer is a journey fraught with both hope and caution. Just as a desert traveler must be aware of the potential dangers of the environment, healthcare professionals and patients must carefully navigate the risks and benefits of cancer treatments. This study sheds light on the potential cardiovascular side effects of pazopanib, providing valuable information to guide informed decision-making in cancer care.

Date :
  1. Date Completed 2019-06-24
  2. Date Revised 2023-10-04
Further Info :

Pubmed ID

29706106

DOI: Digital Object Identifier

NIHMS996861

Related Literature

Article Analysis
・Side Effects of pazopanib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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