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Mucosal delivery systems of antihypertensive drugs: A practical approach in general practice.

Author: BialyLukasz P, Mlynarczuk-BialyIzabela, WojcikCezary

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study explores the possibility of mucosal delivery of antihypertensive drugs as an alternative to oral medication in patients unable to receive oral medication. The authors describe the use of mucosal delivery systems for various antihypertensive drugs including Captopril, Nitrendipine, Metoprolol tartrate, Propranolol and Furosemide, and provide a case report of successful prolonged-term use of these drugs delivered via the mucosal route in a patient with severe hypertension. While the treatment was effective and without side effects, the long-term safety and efficacy of such therapy needs further confirmation through randomized clinical trials.
Paper Details　
Original Abstract of the Article :
Patients who are unable to receive oral medication (p.o.) are a major problem in outpatient settings, especially in home health care systems. Mucosal administration of drugs offers an alternative to the oral route, especially when the parenteral mode cannot be used. There are three main pathways of ...See full text at original site
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引用元：
https://doi.org/10.5507/bp.2018.022

データ提供：米国国立医学図書館（NLM）

Mucosal Delivery Systems: A Novel Approach to Antihypertensive Treatment

For patients who struggle to swallow oral medications, the traditional route of drug delivery can be a challenging desert to navigate. This research explores the potential of mucosal delivery systems as an alternative for delivering antihypertensive medications, offering a new path towards effective treatment. The authors examine the various mucosal pathways, including sublingual/buccal, intranasal, and rectal, and discuss their suitability for delivering different antihypertensive drugs.

Mucosal Delivery: A Promising Alternative for Antihypertensive Treatment

The research highlights the potential of mucosal delivery for specific antihypertensive medications, such as perindopril arginine, amlodipine besylate, captopril, nitrendipine, metoprolol tartrate, propranolol, and furosemide. The authors provide a practical approach for general practitioners, outlining the pharmacokinetic considerations for each drug and illustrating the potential benefits of mucosal delivery with a case report of a patient successfully managed using this method.

Navigating the Landscape of Drug Delivery

This research opens up new possibilities in the realm of drug delivery, offering a more patient-centered approach for those who struggle with oral medications. It emphasizes the need for continued research to further explore the efficacy and safety of mucosal delivery systems for various medications, paving the way for more effective and personalized treatment options.

Dr.Camel's Conclusion

This research points to a new oasis in the vast desert of drug delivery, offering a refreshing alternative for patients who struggle with traditional routes. Mucosal delivery holds the potential to revolutionize the way we administer medications, leading to more personalized and effective treatments.

Date :
  1. Date Completed 2018-11-15
  2. Date Revised 2018-11-15
Further Info :

Pubmed ID

29765168

DOI: Digital Object Identifier

10.5507/bp.2018.022

SNS
PICO Info
in preparation
Languages

English

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