Paper Details 
Original Abstract of the Article :
Group B Streptococcus (GBS) clinical isolates with reduced penicillin susceptibility (PRGBS) have emerged through acquisition of amino acid substitutions in penicillin-binding protein 2X (PBP2X). Moreover, we also reported the emergence of penicillin-susceptible GBS clinical isolates with reduced ce...See full text at original site
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引用元:
https://doi.org/10.1007/s10096-018-3278-7

データ提供:米国国立医学図書館(NLM)

Penicillin-Susceptible Group B Streptococcus: A Rising Threat in Japan

The world of [infectious disease] is constantly evolving, with new strains of bacteria emerging and adapting to antimicrobial treatments. This study examines the prevalence and multidrug resistance patterns of [penicillin-susceptible Group B Streptococcus (GBS)] with [reduced ceftibuten susceptibility] in Japan. The authors investigated the isolation rate and multidrug resistance tendency of these GBS strains, highlighting a growing public health concern.

The Emergence of a New GBS Threat

The study found a significant isolation rate of [7.2%] for [ceftibuten-resistant penicillin-susceptible GBS (CTBr PSGBS)] strains in Japan. This finding suggests that CTBr PSGBS is emerging as a new threat, posing a potential challenge for effective treatment. Imagine a desert traveler encountering a group of venomous snakes. These snakes, like CTBr PSGBS, pose a significant threat, demanding careful attention and appropriate measures to protect against potential harm.

Multidrug Resistance: A Growing Concern

The study also revealed a high [51.9%] rate of [resistance and non-susceptibility] to [macrolides and fluoroquinolones] among CTBr PSGBS strains. This indicates a trend towards multidrug resistance, highlighting the importance of careful antimicrobial stewardship and the need for continued surveillance to track the emergence of new resistant strains. This research is like a desert oasis that has been overgrazed by camels. The oasis, once abundant with resources, has become depleted, mirroring the situation with antibiotics. Overuse and improper use of antibiotics can lead to the emergence of multidrug-resistant strains, diminishing the effectiveness of these life-saving medications.

Dr.Camel's Conclusion

This study emphasizes the importance of ongoing surveillance and antimicrobial stewardship to combat the emergence of drug-resistant bacteria. The findings highlight the need for healthcare professionals to be vigilant in tracking the evolution of GBS strains and adapting treatment strategies to ensure effective management of these infections. This research is like a camel caravan traversing a vast desert: The caravan leader must be prepared for potential challenges and adapt their strategy based on the changing landscape to ensure a successful journey.

Date :
  1. Date Completed 2018-11-08
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

29770902

DOI: Digital Object Identifier

10.1007/s10096-018-3278-7

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Languages

English

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