Successful treatment of fulminant neonatal enteroviral myocarditis in monochorionic diamniotic twins with cardiopulmonary support, intravenous immunoglobulin and pocapavir.

Author: AmdaniShahnawaz M, JohnAudrey Odom, KimHannah S, OrvedahlAnthony, SaidAhmed, SimpsonKathleen

Paper Details 
Original Abstract of the Article :
Neonatal cardiogenic shock most commonly occurs due to critical congenital heart disease, sepsis, metabolic disorder or arrhythmias. In particular, enterovirus infections are common in the neonatal period, and patients can present with fulminant myocarditis. Early recognition is imperative due to it...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965763/

データ提供:米国国立医学図書館(NLM)

Fulminant Neonatal Enteroviral Myocarditis: A Case Study of Successful Treatment

This research presents a case report of successful treatment of fulminant neonatal enteroviral myocarditis in monochorionic diamniotic twins. Neonatal cardiogenic shock, a life-threatening condition, can occur due to various factors, including enterovirus infections. The authors detail the use of cardiopulmonary support, intravenous immunoglobulin, and pocapavir, an enteroviral capsid inhibitor, in managing these twins' severe myocarditis.

A Tale of Two Twins: Navigating the Desert of Neonatal Myocarditis

The case report describes the successful treatment of fulminant neonatal enteroviral myocarditis in identical twins. Both twins received similar interventions, including cardiopulmonary support, intravenous immunoglobulin, and pocapavir. The twins experienced remarkable recovery within two weeks, highlighting the potential benefit of pocapavir in treating severe enteroviral infections. While the specific contribution of each intervention is difficult to assess, the case provides evidence for the effectiveness of this multi-faceted approach in managing this challenging condition.

Hope for Neonatal Myocarditis: A Beacon in the Desert of Disease

This case report provides valuable insights into the potential treatment options for fulminant neonatal enteroviral myocarditis. The successful outcome, despite the severity of the condition, offers hope for clinicians managing this complex disease. The study underscores the importance of early diagnosis, aggressive intervention, and potentially new antiviral therapies like pocapavir in improving outcomes for infants with this life-threatening condition. It is a reminder that even in the face of seemingly insurmountable challenges, medical advancements can bring hope and healing to the most vulnerable patients.

Dr.Camel's Conclusion

This case report demonstrates the potential benefits of a multi-faceted approach to treating fulminant neonatal enteroviral myocarditis, offering hope for clinicians facing this challenging condition. The successful outcomes for these twins underscore the importance of early diagnosis, aggressive intervention, and potentially new antiviral therapies like pocapavir in improving outcomes for infants with this life-threatening condition.

Date :
  1. Date Completed 2018-10-11
  2. Date Revised 2020-05-18
Further Info :

Pubmed ID

29776940

DOI: Digital Object Identifier

PMC5965763

Related Literature

SNS
PICO Info
in preparation
Languages

English

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