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Original Abstract of the Article :
To review the most recent data on the development of endothelin receptor antagonists (ERAs) for the treatment of hypertension and the management of diabetic nephropathy RECENT FINDINGS: Recent reviews and meta-analyses of experimental and clinical data obtained with ERAs confirmed that endothelin re...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s11906-018-0848-0
データ提供:米国国立医学図書館(NLM)
Endothelin Receptor Antagonists: A Potential Weapon in the Fight Against Hypertension
The study explores the role of endothelin receptor antagonists (ERAs) in managing hypertension, a common and serious cardiovascular condition. Researchers reviewed the latest data on the development and use of ERAs for treating hypertension and diabetic nephropathy. They found that ERAs can effectively lower blood pressure, but their use is sometimes limited by potential side effects.
ERAs: A Promising Strategy for Blood Pressure Control
The study highlights the potential benefits of ERAs for managing hypertension. ERAs effectively lower blood pressure in patients with essential and resistant hypertension. This suggests that ERAs can be a valuable tool for treating individuals who do not respond well to other antihypertensive medications. It's like discovering a new oasis in the desert, offering a fresh solution for managing hypertension.
Addressing Side Effects and Future Research
The study acknowledges that ERAs can cause side effects, including fluid retention and liver toxicity. These side effects have limited the use of ERAs in some cases. However, researchers are continuing to investigate new ERA drugs with improved tolerability profiles. Just like a desert traveler must be cautious of potential dangers, researchers are working to overcome the challenges associated with ERAs to maximize their benefits.
Dr.Camel's Conclusion
This study provides a comprehensive overview of ERAs, emphasizing their potential for managing hypertension. While side effects remain a concern, ongoing research is paving the way for safer and more effective ERA therapies. It's like the desert, constantly changing and offering new opportunities for exploration and discovery. ERAs represent a promising avenue for addressing hypertension, and continued research will help us navigate this complex landscape to improve cardiovascular health.
Date :
- Date Completed 2019-07-15
- Date Revised 2019-07-15
Further Info :
Related Literature
English
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