Efficacy and Safety of Oral NEPA (Netupitant/Palonosetron), the First Fixed-Combination Antiemetic, in Patients With Gynecological Cancers Receiving Platinum-Based Chemotherapy.

Author: BorroniMaria Elisa, BošnjakSnežana M, JordanKarin, RizziGiada, StamatovicLjiljana

Paper Details 
Original Abstract of the Article :
Patients with gynecological cancers are at high risk for chemotherapy-induced nausea and vomiting (CINV) after platinum-based chemotherapy (CT). NEPA (300-mg netupitant, 0.50-mg palonosetron) is the first oral fixed-combination antiemetic. Pivotal trials demonstrated the superiority of oral NEPA ove...See full text at original site
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引用元:
https://doi.org/10.1097/IGC.0000000000001292

データ提供:米国国立医学図書館(NLM)

Fighting Nausea and Vomiting: NEPA for Gynecological Cancer Patients

Chemotherapy, a powerful tool used to fight cancer, can have some unpleasant side effects. One of the most common is chemotherapy-induced nausea and vomiting (CINV). It's like a sandstorm sweeping through the body, causing discomfort and making it difficult to recover. Researchers are constantly seeking new ways to combat CINV, especially for patients with gynecological cancers, a group particularly susceptible to this side effect. This study focuses on NEPA, a new antiemetic medication, and its effectiveness in preventing CINV in patients undergoing platinum-based chemotherapy.

NEPA: A New Oasis in the Desert of CINV

NEPA, a combination of netupitant and palonosetron, has been shown to be effective in preventing CINV. This study, which reviewed data from clinical trials, confirmed that NEPA outperformed intravenous palonosetron in preventing CINV in patients with gynecological cancers. It's like finding a hidden spring in the desert, offering a cool and refreshing relief from the harsh side effects of chemotherapy.

Finding Relief from CINV: A Guide Through the Desert

If you're a patient undergoing chemotherapy, you'll want to talk to your doctor about NEPA. They can assess your individual needs and help you make the best decision for your treatment. Finding relief from CINV is a crucial step in your journey through cancer treatment, and NEPA might be the oasis you've been searching for.

Dr.Camel's Conclusion

This study gives us hope that NEPA can be a valuable tool in managing CINV. It's like a beacon shining brightly in the desert, offering a new and promising solution for patients battling this common side effect of chemotherapy.

Date :
  1. Date Completed 2019-06-07
  2. Date Revised 2019-06-07
Further Info :

Pubmed ID

29794499

DOI: Digital Object Identifier

10.1097/IGC.0000000000001292

Related Literature

SNS
PICO Info
in preparation
Languages

English

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